Báo cáo khoa học: Differential membrane compartmentalization of Ret by PTB-adaptor engagement pdf

... molecules with Ret and their function in redistributing Ret to specialized membrane compartments. We found that engagement of Ret with the Frs2 adaptor results in an enrichment of Ret in lipid ... results in distinctly different patterns of plasma membrane localization of Ret. Frs2 recruitment resulted in a concentration of Ret into membrane foci [4,11]. The Ret...

Ngày tải lên: 07/03/2014, 05:20

... body, gut of mated queens and abdomen of adult males were ana- lyzed by western blotting. To compare receptor expression between virgin and mated queens (Figs 2–4), membranes of four pairs of ovaries ... contained 2 lL of the diluted cDNA (1 : 2), 0.4 lm of each primer, 400 lm of dNTPs, 1 · reaction buffer and 0.4 lL Taq DA polymerase in a final volume of 20 lL. PCR amplificat...

Ngày tải lên: 18/02/2014, 08:20

... of size, to form a stochastic tree-substitution grammar (STSG). Since a parse tree of a sentence may be generated by several (leftmost) derivations, the probability of a tree is the sum of ... advantage of U-DOP* over UML-DOP is that it works with a more succinct grammar extracted from the shortest derivations of HC. Table 2 shows the size of the grammar (number of r...

Ngày tải lên: 20/02/2014, 12:20

... the number of hits returned by a search engine, with a query consisting of the word and one of seed words (e.g., “word NEAR good”, “word NEAR bad”). They re- garded the difference of two association ... orientations of words are determined according to the averages values of the spins. Despite the heuristic flavor of this deci- sion rule, it has a theoretical background related...

Ngày tải lên: 20/02/2014, 15:20

... versions of these two isoforms, as well as of the Mxi1-WR isoform that lacks the SID, and shown to give rise to proteins of the expected size expressed at similar levels (Fig. 1A). Each of these ... 4B). The finding of these differential functions is in line with the dogma that the proteome gains functional complexity by encoding multiple isoforms of a given protein, with these...

Ngày tải lên: 18/02/2014, 16:20

... (18 °C) temperatures leads to differential expression of alternative forms of the LDH-A gene in white skeletal muscle of weatherfish, Misgurnus fossilis. Two isoforms of LDH-A mRNA were isolated ... or excess of kinetic energy (as a measure of temperature) and its effect on enzyme activity. Alternatively, we know of a number of examples of qualitative strategies, for exampl...

Ngày tải lên: 19/02/2014, 02:20

... mitochondrial outer membrane shares many features with bacterial outer membranes [1,2]. Polypeptides embedded in the outer membrane of Gram-negative bacteria are either lipoproteins anchored by a covalently ... outer membrane of mitochondria comes from the b-barrel or a-helical type integral membrane proteins. To identify and characterize a-helical type integral membrane prote...

Ngày tải lên: 19/02/2014, 07:20

... protein) of YYY49 and YYT42 con- tained approximately 1 and 2 ng of hHSF2, and those of YYT50 and YYT17 contained approximately 0.01 and 0.1 ng of hHSF4, as judged by the intensity of each band. ... recognition by human HSFs N. Yamamoto et al. 1974 FEBS Journal 276 (2009) 1962–1974 ª 2009 The Authors Journal compilation ª 2009 FEBS Differential recognition of heat shock elem...

Ngày tải lên: 07/03/2014, 00:20

... ultrasound of the thorax in case of pleural effusion on the CXR, start or change in medication (diuretics); insertion of a pleural drain; and repositioning of devices in the case of mal- position of ... performance of a bronchoalveolar lavage for culture, or start of or a change in antimicrobial therapy in case of unex- pected infiltrates on the CXR; repositioning of tubes...

Ngày tải lên: 25/10/2012, 10:39

... Discussion Inhibition of proteases by MA It has been previously proposed that MA may inhibit the activity of proteases of T. gondii [14] and HIV [12,31]. To ascertain the inhibition range of MA on the ... proteolytic hydrolysis of haemoglobin as a source of amino acids constitutes one of the essential processes which take place along the intra-erythrocytic stage of the paras...

Ngày tải lên: 14/02/2014, 14:20