Báo cáo khoa học: Synthesis and characterization of a new and radiolabeled high-affinity substrate for H+/peptide cotransporters pdf

Tài liệu Báo cáo khoa học: NMR structural characterization of HIV-1 virus protein U cytoplasmic domain in the presence of dodecylphosphatidylcholine micelles doc

Tài liệu Báo cáo khoa học: NMR structural characterization of HIV-1 virus protein U cytoplasmic domain in the presence of dodecylphosphatidylcholine micelles doc

... the aqueous buffer. Qualitative analysis of secondary chemical shift and paramagnetic relaxation enhancement data in conjunction with dynamic information from heteronuclear NOEs and structural ... the calculated structures was acceptable; 89% of the analysed backbone torsions fell into the most favoured and additionally allowed regions of the Rama- chandran plot. An additional 6%...

Ngày tải lên: 18/02/2014, 06:20

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Tài liệu Báo cáo khoa học: "Arabic Tokenization, Part-of-Speech Tagging and Morphological Disambiguation in One Fell Swoop" pdf

Tài liệu Báo cáo khoa học: "Arabic Tokenization, Part-of-Speech Tagging and Morphological Disambiguation in One Fell Swoop" pdf

... Buckwalter Arabic Morphological Analyzer, but (in analysis mode) produces an output in the lexeme -and- feature format (which we need for our approach) rather than the stem -and- affix format of the Buckwalter ... system of affixation and clitics and the omission of disam- biguating short vowels and other orthographic di- acritics in standard orthography (“undiacritized or- thogra...

Ngày tải lên: 20/02/2014, 15:20

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Báo cáo khoa học: Functional classification of scaffold proteins and related molecules pptx

Báo cáo khoa học: Functional classification of scaffold proteins and related molecules pptx

... that are important in pathways activated by internal signals, such as DNA damage, e.g. MDC1 in DNA doule-strand breaks [20] and BRCA1 in many cellular pathways including DNA repair [29]. In a ... proteins). This classification has both advantages and limita- tions. Its major advantage is simplification, because it enables one to think in terms of a few concepts instead of a practi...

Ngày tải lên: 06/03/2014, 22:21

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Tài liệu Báo cáo khoa học: C-Terminal extension of a plant cysteine protease modulates proteolytic activity through a partial inhibitory mechanism doc

Tài liệu Báo cáo khoa học: C-Terminal extension of a plant cysteine protease modulates proteolytic activity through a partial inhibitory mechanism doc

... proteases [Erv -A, -B and –C (isolated from the latex of Ervatamia coronaria in our laboratory) and papain from Carica papaya (Merck, Kenilworth, NJ, USA)], two serine proteases [trypsin and chymotrypsin ... CT ex 114 aa 208 aa 24 aa BamH 34 aa Start Stop Xho1 N -Pro Protease domain Protease domain CT - ex 380 aa 1 II NP 114 aa 208 aa BamH1 34 aa Start Stop Xho1 SS SS G SSS S N-Pro 35...

Ngày tải lên: 14/02/2014, 14:20

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Tài liệu Báo cáo khoa học: Intrinsic GTPase activity of a bacterial twin-arginine translocation proofreading chaperone induced by domain swapping ppt

Tài liệu Báo cáo khoa học: Intrinsic GTPase activity of a bacterial twin-arginine translocation proofreading chaperone induced by domain swapping ppt

... Tat proofreading and TMAO reductase activity assays The signal peptide binding-dependent Tat proofreading activity of TorD can be isolated and assayed in vivo,as described previously [5]. Strain ... GTPase activity (Fig. 1B). Titration of increasing amounts of MgCl 2 gradually enhances GTPase activity, with a peak at approximately 1 mm (Fig. 1B). The malachite green assay was also...

Ngày tải lên: 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: Structure-activity relationships of a-conotoxins targeting neuronal nicotinic acetylcholine receptors ppt

Tài liệu Báo cáo khoa học: Structure-activity relationships of a-conotoxins targeting neuronal nicotinic acetylcholine receptors ppt

... mutational analysis has been carried out on ImI, PnIA, PnIB and to a lesser extent on GID and MII. Analysis of ImI has revealed that Asp5-Pro6-Arg7 and Trp10 are important for biological activity ... of Queensland, Brisbane, QLD, Australia a- Conotoxins that target the neuronal nicotinic acetylcho- line receptor have a range of potential therapeutic applica- tions and are...

Ngày tải lên: 19/02/2014, 12:20

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Tài liệu Báo cáo khoa học: Novel aggregate formation of a frame-shift mutant protein of tissue-nonspecific alkaline phosphatase is ascribed to three cysteine residues in the C-terminal extension pdf

Tài liệu Báo cáo khoa học: Novel aggregate formation of a frame-shift mutant protein of tissue-nonspecific alkaline phosphatase is ascribed to three cysteine residues in the C-terminal extension pdf

... fraction). BSA (b, 68 kDa), alcohol dehydrogenase (a, 141 kDa) and catalase (250 kDa) were loaded on to a separate gradient as mole- cular mass markers. K. Komaru et al. Novel aggregate formation of an alkaline ... Inactiva- tion of two mouse alkaline phosphatase genes and establishment of a model of infantile hypophosphatasia. Dev Dyn 208, 432–446. K. Komaru et al. Novel agg...

Ngày tải lên: 19/02/2014, 17:20

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Tài liệu Báo cáo khoa học: Site-directed mutagenesis of a loop at the active site of E1 (a2b2) of the pyruvate dehydrogenase complex A possible common sequence motif docx

Tài liệu Báo cáo khoa học: Site-directed mutagenesis of a loop at the active site of E1 (a2b2) of the pyruvate dehydrogenase complex A possible common sequence motif docx

... DCPIP assay, the E1aY28 1A and E1aR28 2A mutants displayed a catalytic activity about twice that of wild-type E1. The single mutants E1aR26 7A and E1aD27 6A and the multiple mutants E1aY28 1A/ R28 2A/ S28 3A ... 16-fold molarexcessofdi-domainoverE1.Lane1:E1wild-type;lane2:E1 wild-type + di-domain; lane 3: E1aF26 6A mutant; lane 4: E1aF26 6A mutant + di-domain; lane 5: E1aR26...

Ngày tải lên: 20/02/2014, 23:20

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Tài liệu Báo cáo khoa học: Physico-chemical characterization and synthesis of neuronally active a-conotoxins docx

Tài liệu Báo cáo khoa học: Physico-chemical characterization and synthesis of neuronally active a-conotoxins docx

... identification of post-translational modifications Isolation and identification Standard procedures for identification and isolation of a- conotoxins generally incorporate separations using reversed-phase ... ambiguities arising from, for example, asparagine to aspartic acid, or glutamine to glutamic acid changes [14]. The a- conotoxins EpI, PnIA, GIC, GID, AnIA and AnIB contain p...

Ngày tải lên: 19/02/2014, 12:20

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Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

... picolinic acid (PA), quinolinic acid (QA) and NAD homeostasis. Indeed, the enzyme stands at a branch point of the tryptophan to NAD pathway, and deter- mines the final fate of the amino acid, i.e. transformation ... Walker AL, Iwaki H, Hasegawa Y & Liu A (2005) Kinetic and spectroscopic characterization of ACMSD from Pseudomonas fluorescens reveals a penta- coordinate mo...

Ngày tải lên: 18/02/2014, 06:20

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