... (amino acids 19–43), and four extracellulardomains spanning amino acids 44–150 (domain C), 151– 27 4 (domain D), 27 5–586 (domain E), and 587–750(domain F). While the domain spanning amino acids ... ligand-free protein, the authors docked several GCPIIinhibitors into the GCPII-binding pocket and proposed/analyzed the amino acid residues involved in the ligand–protein interactions. All ... N-benzyloxycarbonyl-L-leucinyl-L-leucinyl-L-norvalinal.Enzyme: human glutamate carboxypeptidase II (EC 3.4.17 .21 ).(Received 26 March 20 04, revised 3 May 20 04,accepted 7 May 20 04)Eur. J. Biochem. 27 1, 27 82 27 90...