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Báo cáo khoa học: Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression docx

Báo cáo khoa học: Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression docx

Báo cáo khoa học: Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression docx

... muscles and several cancer cell lines [94].Table 1. Role of nuclear actin- binding proteins interacting with the androgen receptor. AR, androgen receptor; LBD, ligand-binding domain. Actin- bindingproteinTargetingsequence ... ARTICLE Nuclear actin and actin- binding proteins in the regulation of transcription and gene expression Bin Zheng1, Mei Han1, Michel Bernier2 and Jin-kun Wen11 Department of Biochemistry and ... that actin is associated withrDNA genes, and microinjection of anti -actin Ig into the nuclei of HeLa cells inhibits pre-rRNA synthesis in vivo [25,34]. The interaction of NM1 with actin in the initiation...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "Toward finer-grained sentiment identification in product reviews through linguistic and ontological analyses" ppt

... as shown in (1b). In order to reflect this possibility, we need to adjust the weight of each polarity accordingly. In this paper, we propose to look into the kind of linguistic and ontological ... concept (e.g., the width of the thigh part of the pants) rather than a coarse-grained one (e.g., just the size of the pants). To deal properly with the changing granularity of such concepts, we ... domain specific semi-hierarchical network for clothes of the Clothing-Type structure, in addition to the Review struc-ture, by utilizing hierarchical category informa-tion in online shopping...
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Tài liệu Báo cáo khoa học: A genetic screen identifies mutations in the yeastWAR1 gene, linking transcription factor phosphorylation to weak-acid stress adaptation docx

Tài liệu Báo cáo khoa học: A genetic screen identifies mutations in the yeastWAR1 gene, linking transcription factor phosphorylation to weak-acid stress adaptation docx

... were raised in rabbitsagainst a GST-War1p fusion protein containing 294 aminoacids of the C-terminal part of War1p (amino acids 650–944) fused in- frame to the C-terminus of GST. The gene fusion ... expression of the C-terminal 294 amino acids of WAR1 fused in- frameto the C-terminus of GST. Escherichia coli strain DH5aharboring pCG1950 was grown on 37 °CtoanA600 of 0.5. Expression of the GST-War1p ... about the molecularstructure, as well as the protein–protein and protein–DNA interactions, of this binuclear zinc transcriptionalregulator. The polyclonal antibodies to War1p shouldbe useful in...
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Tài liệu Báo cáo khoa học: An engineered disulfide bridge mimics the effect of calcium to protect neutral protease against local unfolding docx

Tài liệu Báo cáo khoa học: An engineered disulfide bridge mimics the effect of calcium to protect neutral protease against local unfolding docx

... Ger-many). The amount of intact protein was calculated from the intensity of the protein band.Autoproteolysis in sample solutions containing <20lgÆmL)1protein was followed by determining the ... the introduction of the disulfide bridge (at5mm CaCl2 and 25 ° C) is obtained. The in uence of calcium ions on the unfoldingkinetics The in uence of the calcium ion concentration onunfolding ... basis of the X-raystructure of thermolysin by using homologymodeling with the programWHAT IF [5]. The orange sphere indicates the catalytic zincion, and the violet spheres indicate the bound...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "From HOPE en I''''ESPERANCE On the Role of Computational Neurolinguistics in Cross-Language Studies " pptx

... disambiguated word meaning. It is the in interaction of the results of these asynchronous processes that the process of comprehension is defined. The processes are independent of the know- ledge ... but are often generic and mark masculine, feminine, or plural (Gross, 1977; Goffic and McBride, 1975). And furthermore, these same articles often are not translated into meaning preserving sentences ... affected. The study includes off-line picture naming which forces use of articles in all of the above contexts, as well as on-line production of these morphemes in an attempt to determine in which...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "A HYBRID APPROACH TO REPRESENTATION IN THE JANUS NATURAL LANGUAGE PROCESSOR" pot

... defining the set of items that have ever been the actor in a flight. Their definition is solely within NIKL using the QUA link [14], which is exactly the set of fillers of a slot. While having ... expressions in inten- sional logic. 3 4. Use of the Taxonomy in Janus By domain mode/we mean the set of axioms en- coded in NIKL regarding the constants. The domain model serves several purposes in ... 99.9% of the examples in our expert system and data bass applications have fit well within the constraints of NIKL. Based on our experience and that of others, the axioms and limited inference...
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Tài liệu Báo cáo khoa học:

Tài liệu Báo cáo khoa học: "Language Resources Factory: case study on the acquisition of Translation Memories" potx

... help them during the designphase, being able to reuse workflows (or parts of them) and thus avoiding reinveinting the wheel.4 Using the tools to work with NLPAll the aforementioned tools were installed, ... continue processing the rest of the input data if the workflow is robust (i.e. makesuse of retry and parallelisation) and the error isconfined to a WS (i.e. it does not affect the rest of the ... crawl the webpages in the domains and gather pairs of web documents in the target languages that belong to the targetdomain. Second, we apply a sentence aligner.14It takes as input the pairs of...
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Báo cáo khoa học: A novel 2D-based approach to the discovery of candidate substrates for the metalloendopeptidase meprin pot

Báo cáo khoa học: A novel 2D-based approach to the discovery of candidate substrates for the metalloendopeptidase meprin pot

... Critchley DR (1996) Acidicphospholipids inhibit the intramolecular associationbetween the N- and C-terminal regions of vinculin,exposing actin- binding and protein kinase C phosphory-lation sites. ... ECM and intracellular actin cytoskeleton. It wasdemonstrated that acidic phospholipids inhibit intra-molecular association between the N- and C-terminalregions of vinculin, exposing actin- binding ... targeted regulation of ECM assembly.Vinculin is an actin- binding protein localized on the cytoplasmic face of integrin-mediated cell-ECM junc-tions designated as focal adhesions [25]. Vinculin stabi-lizes...
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Tài liệu Báo cáo khoa học: Nuclear receptors in the mosquito Aedes aegypti Annotation, hormonal regulation and expression profiling ppt

Tài liệu Báo cáo khoa học: Nuclear receptors in the mosquito Aedes aegypti Annotation, hormonal regulation and expression profiling ppt

... blocked. The presence of 20E,however, favors the formation of the AaEcR⁄ AaUSPheterodimer [13], indicating that the regulation of the activity of these proteins occurs through protein–pro-tein interactions, ... processes. In A. aegypti, the discrete expression of both AaHR3 and AaHR4 suggests their function in the regulatory hierarchy in the mosquito fat body dur-ing vitellogenesis. Indeed, the analysis of the ... reorganization of the follicular epithelium in the resulting adults [40]. DmE75A and DmE75Bhave been implicated in defining the transition stages8 and 9 of the egg chambers through either inducingor...
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Báo cáo khoa học: Nuclear localization of human spermine oxidase isoforms – possible implications in drug response and disease etiology pptx

Báo cáo khoa học: Nuclear localization of human spermine oxidase isoforms – possible implications in drug response and disease etiology pptx

... protec-tive roles of spermine in free radical scavenging and DNA shielding, and resulting in an overall increased potential for oxidative DNA damage in these cells. The results of these studies therefore ... Catalysis of spermine oxidation by human spermine oxi-dase. SMO catalyzes the cleavage of spermine, resulting in back-conversion to spermidine, and the generation of 3-aminopropanal and H2O2.Cellular ... SMO isoforms in a mouse neuroblastoma line. The cell lines created in the present study, however, represent the first stableoverexpression of any of the human spermine oxidaseisoforms in human...
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