Báo cáo khoa học: NF-jB regulates the transcription of protein tyrosine kinase Tec pdf
Báo cáo khoa học: NF-jB regulates the transcription of protein tyrosine kinase Tec pdf
... expression of the Tec tyrosine kinase. NF-jB binds directly to the Tec promoter and induces Tec transcription The above results show that both proteasome and NF-jB inhibitors can suppress the transcriptional activity ... when NF-jB bind- ing site a was mutated, the baseline Tec promoter transcription activity decreased. Thus Tec- 420M had 67% of the activ...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: Vps4 regulates a subset of protein interactions at the multivesicular endosome doc
... Vps4p ATP binding. Studying the role of Vps4p in the regulation of protein protein inter- actions at the MVB will lead to a better understanding of the mechanism of MVB sorting and virus budding. Experimental ... ª 2007 The Authors Journal compilation ª 2007 FEBS of a ubiquitin molecule, is followed by sequential recruitment of components of the MVB sorting machine...
Ngày tải lên: 23/03/2014, 09:20
Báo cáo khoa học: Evidence for the presence of ferritin in plant mitochondria pdf
... possess at the N-terminus the typical presequences of the chloroplastic protein transit peptide [28], similarly to what reported for pea ferritin [29,30]. On the other hand, the analysis of the presequence ... the immunodecoration show a d ecrease of approximately 50% in the Mpl proteins. On the other hand, the immunodec- oration of PMt and Mpl proteins with anti...
Ngày tải lên: 16/03/2014, 18:20
Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf
... bc 1 sub-complex, but the presence of only one of these two subunits does not substitute for the other. After the addition of ISP, the binding of the last subunit (i.e. Qcr10p) finally occurs. These find- ings ... also unknown. Furthermore, as in the case of the biogene- sis of other multi-subunit complexes of the mitochon- drial respiratory chain, the assistance...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Looking for the ancestry of the heavy-chain subunits of heteromeric amino acid transporters rBAT and 4F2hc within the GH13 a-amylase family ppt
... Some of these features can be traced in the sequences of hcHAT1 and hcHAT2 groups as well as of the ATG proteins (Fig. 2), indicating evolutionary relationships of all these enzymes and proteins ... is the lack of domain B protruding out of the TIM barrel in the place of loop 3 connecting the b3-strand to the a3-helix [9,21]. Sharing domain B by rBATs and GH13 enzy...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Insights into the structure of plant a-type phospholipase D Susanne Stumpe, Stephan Konig and Renate Ulbrich-Hofmann ¨ ppt
... constants in the range of 0.5 mm were estimated from isothermal titration calorimetry [36]. The C2 domains of other proteins showed cal- cium-binding affinities in the range of 1–50 lm [37,38]. As the ... the typical range for a spherical particle. The bell-shaped distance distribution function illustrates the quality of the experimental data (Fig. 2B). Reconstruction...
Ngày tải lên: 19/02/2014, 02:20
Tài liệu Báo cáo khoa học: Hypoxia reduces the expression of heme oxygenase-2 in various types of human cell lines A possible strategy for the maintenance of intracellular heme level pdf
... degrada- tion in the population of hemoglobin-positive cells. To the best of our knowledge, there has been no report on the promoter function of the human HO-2 Fig. 7. Characterization of the human ... of the transcription start sites. The upstream region of the HO-2 gene is shown. Exon 1 encodes the untranslated region, and exon 2 encodes the protein- codin...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: Insights into the interaction of human arginase II with substrate and manganese ions by site-directed mutagenesis and kinetic studies Alteration of substrate specificity by replacement of Asn149 with Asp docx
... as a consequence of the mutagenic replacements. Effects of the His120Asn and His145Asn mutations on the affinity of metal binding to arginase II To further examine the effects of the His120fiAsn and ... addition to removal of the more weakly bound Mn 2+ , the lower affinity for that more tightly bound to the protein may explain the absence of Mn 2+ from the EDTA...
Ngày tải lên: 20/02/2014, 02:21
Báo cáo khoa học: Studies on the role of the receptor protein motifs possibly involved in electrostatic interactions on the dopamine D1 and D2 receptor oligomerization pdf
... from the different localization of these proteins in the cell. The molecular mechanisms underlying the transport processes of GPCRs from the ER to the cell surface have recently become the subject ... prevents the export of proteins to the plasma membrane. There are three types of retention motifs identified in the cytosolic domains of various proteins: KDEL, KKXX...
Ngày tải lên: 07/03/2014, 03:20
Báo cáo khoa học: Investigations into the ability of an oblique a-helical template to provide the basis for design of an antimicrobial anionic amphiphilic peptide pot
... contribute to the susceptibility of E. coli model membranes to the action of AP1. An important determinant of the susceptibility of membranes to a-AMPs is the packing characteristics of the individual ... stable in the presence of AP1, further supporting the sugges- tion that this instability may contribute to the susceptibility of E. coli to the antimicrobial...
Ngày tải lên: 07/03/2014, 12:20