Báo cáo khoa học: Assembly of nuclear DNA-encoded subunits into mitochondrial complex IV, and their preferential integration into supercomplex forms in patient mitochondria doc

... compilation ª 2009 FEBS 6713 Assembly of nuclear DNA-encoded subunits into mitochondrial complex IV, and their preferential integration into supercomplex forms in patient mitochondria Michael Lazarou 1 , ... imported complex IV subunits can integrate into complex IV and its supercomplexes by associating with pre-existing subunits and integra...

Ngày tải lên: 07/03/2014, 00:20

... the ER extract of PSG cells of a normal-level fibroin-producing silkworm Table 2. Determination of molar ratios of H-chain, L-chain, and fhx/P25 in the fibroin secreted into cocoons of a normal breed ... glycoprotein [28,29], in uenza virus hemagglutinin [30,31], and IgM [32] in ER, a further role of N-linked oligosacharide chains of fhx/P25 in the process of assem...

Ngày tải lên: 16/03/2014, 16:20

... acid and docosahexaenoic acid, which are found in fish oil, downregulate LPS- induced NF-jB DNA binding and p65–NF-jB expression, and increase IjBa expression and doco- sahexaenoic acid and ⁄ ... (Fig. 2). Effects of CRLPs on cytokine and chemokine secretion and mRNA expression in macrophages We initially examined the effects of CRLPs on the release of TNFa, IL-6, IL-1b...

Ngày tải lên: 23/03/2014, 04:20

... pS2 gene. In the initial experiments the increase of acetylation of histone H3 and H4 at ER-regulated cathepsin D and pS2 promoters was observed within 10 min of estrogen treatment, peaking at 1 ... (5-aza-2¢-deoxycyti- dine, 5Aza-dC) results in a loss of methylation, loss of BRM and MeCP2 binding and reactivation of tran- scription [174]. In cancer cells, changes i...

Ngày tải lên: 28/03/2014, 22:21

... FIH binding To understand the interplay between HIF-1a, FIH, and IjBa, we coexpressed these proteins in HEK293 cells and examined protein interactions by performing immunoprecipitation and immunoblotting ... interactions with ASB4 and Notch-1. By using yeast two-hybrid screening, Ratcliffe et al. identified two ARD-containing proteins, p105 and uveal autoantigen with coiled-coil do...

Ngày tải lên: 29/03/2014, 23:20

... using pepsin. Pepsin cleaves in the telopeptide domains of type II collagen and in the noncollagenous domains of the minor collagens, type XI and IX, but leaves their triple helical domains intact. ... to interfere with the interactions needed to form cross-links and mature them into trivalent pyridinoline residues. In addition, using antibodies that recognize specific cros...

Ngày tải lên: 31/03/2014, 07:20

... have indi- cated that the CagA PY -induced cell elongation pheno- type also involves tyrosine dephosphorylation of cortactin, vinculin and ezrin, which are three well- known actin-binding proteins ... the amount of intracellu- lar CagA PY . Cortactin, ezrin and vinculin are all Src substrates, and Src inactivation causes dephosphoryla- tion of these proteins and is crucial for t...

Ngày tải lên: 14/02/2014, 19:20

... pheromones to elicit a mating response in cells of the opposite mating type. Cdc42 is involved in pheromone signal- ling that eventually results in G 1 arrest and the for- mation of a mating projection ... formation of a mating projection [28]. Furthermore, homologues of oxysterol- binding proteins, a family of proteins that regulate the synthesis and transport of sterol...

Ngày tải lên: 18/02/2014, 13:20

... sulfo- bromophthalein to rat and human ligandins: characteri- zation of a binding-site peptide. Biochim Biophys Acta 955, 296–300. 52 Gregus Z & Klaassen CD (1982) Role of ligandin as a binding protein and ... anthocyanin sequestration, is a flavonoid- binding protein. Plant Physiol 123, 1561–1570. 24 Grotewold E (2004) The challenges of moving chemicals within and out of cel...

Ngày tải lên: 20/02/2014, 01:20

... Analysis of two CBP (cAMP-response-element-binding protein-binding protein) interacting sites in GRIP1 (glucocorticoid receptor-interacting protein), and their importance for the function of GRIP1. ... conserved AF-2 domain of NRs [22]. The C-terminal region of the p160 co-activa- tor can interact with the AF-1 domain of some NRs and enhance their AF-1 activities in the...

Ngày tải lên: 07/03/2014, 12:20