Báo cáo khoa học: Identification of the amniotic fluid insulin-like growth factor binding protein-1 phosphorylation sites and propensity to proteolysis of the isoforms docx
Báo cáo khoa học: Identification of the amniotic fluid insulin-like growth factor binding protein-1 phosphorylation sites and propensity to proteolysis of the isoforms docx
... 2009 FEBS Identification of the amniotic fluid insulin-like growth factor binding protein-1 phosphorylation sites and propensity to proteolysis of the isoforms Lorenzo Dolcini 1 , Alberto Sala 1 , ... variety of important physi- ological processes. Upon binding they regulate the availability of both insulin-like growth factors I and II (IGF-...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: Identification of the structural determinant responsible for the phosphorylation of G-protein activated potassium channel 1 by cAMP-dependent protein kinase pdf
... Xenopus oocytes. Furthermore, this phosphorylation was regulated by cytosolic injections of PKA activators and inhibitors, suggesting it to be the basis for the functional effects of cAMP injections ... vivo treatment of the oocytes with a PKA inhibitor and also in untreated oocytes. On the other hand, the in vitro phosphorylation signal was markedly dimin- ished whe...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: Identification of the heparin-binding domains of the interferon-induced protein kinase, PKR pptx
... positions of PKR mutants and the mutant name is shown at the bottom of the panels. (C) dsRNA -binding activity of the mutants. The dsRNA -binding activity of the point mutants was tested by their binding ... change, unmasking the ATP -binding site and leading to autophosphorylation of PKR. Activated PKR then phos- phorylates the a-subunit of the protei...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: Identification of the N-terminal region of TjZNT2, a Zrt⁄Irt-like protein family metal transporter, as a novel functional region involved in metal ion selectivity ppt
... with the exception of the N-terminus and the TM III–IV loop. To examine the functions of TjZNT1 and TjZNT2, these transporters were tagged with hemagglutinin (HA) at their N-termini to verify their ... However, the approach lead to the identification of the extracellu- lar N-terminus as a substrate selector in TjZNT2. On alignment of the amino acid sequences...
Ngày tải lên: 29/03/2014, 00:20
Báo cáo khoa học: Identification of the N-termini of NADPH : protochlorophyllide oxidoreductase A and B from barley etioplasts (Hordeum vulgare L.) ppt
... contains a Pchlide binding site [22,26], and that binding of Pch- lide to pPORA is essential for import into the etioplast stroma. The transit peptide of PORA is the only exam- ple of a precursor ... according to our find- ings, amino acids T56–G60 of PORA are located exclusively in the mature part of the PORA protein and not in the transit peptide. The posi...
Ngày tải lên: 30/03/2014, 02:20
Báo cáo khoa học: Identification of the epitope of a monoclonal antibody that disrupts binding of human transferrin to the human transferrin receptor pptx
... restricted to a surface patch of hTF consisting of residues 365–385. Mutagenesis of the F11 epitope of hTF to the sequence of either mouse or pig TF confirmed the identity of the epitope as immunoreactivity ... protein and hTF bind to the same or closely overlapping sites [14] adds further support for the role of the helical domain of the TFR in bindi...
Ngày tải lên: 30/03/2014, 11:20
Báo cáo khóa học: Identification of a gene encoding Lon protease from Brevibacillus thermoruber WR-249 and biochemical characterization of its thermostable recombinant enzyme pptx
... as the standards and their elution volumes, V e , were deter- mined. The standard curve was plotted with the logarithm of molecular mass against V e /V 0 of the standard protein. Peptidase and ... their translocation into the cavity of the cylinder of the proteins themselves [14]. In the past decade, although ATP-dependent proteases of the AAA + superfamily hav...
Ngày tải lên: 16/03/2014, 16:20
Tài liệu Báo cáo khoa học: Identification of differentially expressed genes of the Pacific oyster Crassostrea gigas exposed to prolonged thermal stress docx
... but slightly less and later in mantle. One inducible and two constitutive isoforms of HSP70 are synthesized in the gills and mantle of C. gigas [26]. The expression level of the constitutive forms ... transcription cofactor that inhibits activation of AP-1 transcription factors. QM protein is implicated in the conversion of a broad vari- ety of extracellular signal...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Identification of different isoforms of eEF1A in the nuclear fraction of human T-lymphoblastic cancer cell line specifically binding to aptameric cytotoxic GT oligomers ppt
... belonging to the GTP- binding elongation factor family, which promotes the GTP- dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis and the capture of deacylated ... the cytoplasm, a considerable fraction of the a subunit can be found either in the cytoplasm or the nucleus [35,36]. The involvement of eEF1A in the...
Ngày tải lên: 21/02/2014, 00:20
Báo cáo khoa học: Identification of multiple isoforms of the cAMP-dependent protein kinase catalytic subunit in the bivalve mollusc Mytilus galloprovincialis potx
... article was to investigate the possible existence of different isoforms of the PKA C-subunit in the sea mussel M. galloprovincialis. Results Separation of different isoforms of the C-subunit In order to ... activity of the C-subunit. The transitory increase of cAMP levels inside the cell, induced by an extracellular signal, and the binding of cyclic n...
Ngày tải lên: 07/03/2014, 06:20