Báo cáo khoa học: Amyloid oligomers: formation and toxicity of Ab oligomers ppt

... characteristics of Ab oligomers and their formation mechanism remain unclear. Structure and size of soluble Ab oligomers Many types of natural and synthetic Ab oligomers of different sizes and shapes ... elucidate the mechanism of formation of Ab oligomers. Possible mechanism of soluble oligomer formation and toxicity The mechanism of formati...

Ngày tải lên: 06/03/2014, 09:22

... 85% inhibition of BHLmL2 and BHAb, respectively, while 1 mm 2-mer- captoethanol caused 85% and 97% inhibition of BHLmL2 and BHAb, respectively. The influence of pH on the activities of the BH enzymes ... molecular mass of about 120 kDa. Thus, these data suggest that native BHAb is a dimer. Identification and chemical modification of the purified enzymes To identify BHLmL2 and...

Ngày tải lên: 18/02/2014, 14:20

... be able to transfer protons [31]. However, without an overexpression approach of RpCAbr and RpCAtr, we cannot know the functional effect of changes of some key amino-acids. Origin and number of ... fluorochrome labeling of the probes was chosen to detect RpCAbr mRNAs and RpCAtr mRNAs by green and red fluorescence, respectively. The antisense RpCAbr probe was synthesized by inc...

Ngày tải lên: 18/02/2014, 16:20

... (A) Expanded view of peaks at m ⁄ z 2800.36 and 2832.35 and the fragmentation of the peak at m ⁄ z 2800.36. (B) Expanded view of peaks at m ⁄ z 2934.36 and 2950.35 and the fragmentation of the ... C53S 2-Cys Prx. Expanded view of peaks at m ⁄ z 2800.36 and 2832.35 and the fragmentation of the peak at m ⁄ z 2832.35. 2-Cys Prx was digested with trypsin and prepared for...

Ngày tải lên: 18/02/2014, 17:20

... preparation of complex II. The four subunits of complex II are labeled on the left, and the positions of molecular weight standards are indicated on lane 2. X. Huo et al. Characterization of respiratory ... requirements of struc- ture determination, we had to measure the gene sequences and full amino acid sequences of the porcine complex II subunits. An abundance of gene seq...

Ngày tải lên: 19/02/2014, 02:20

... 23S.5DG b pre-RNA, and the binding of a minimum of n Mg 2+ ions leads to formation of the active complex, whereas binding of a minimum of m Mn 2+ ions forms the inactive complex. The sizes of the active and ... the absolute concentrations; a ratio of Mn 2+ ⁄ Mg 2+ of approxi- mately 1 : 2 or higher inhibited G-dependent cleavage of 23S.5DG b RNA (and self-splicing of...

Ngày tải lên: 19/02/2014, 07:20

... spectrometry and the lability of the sulfogroup in mass spectrometry analysis allows recognition of the modification, and differentiation of sulfotyrosine and phosphotyrosine [38]. Characterization of the ... verification of tyrosine sulfation in a-PnIA and a-PnIB and revision of those sequences were made in an investigation of labile sulfo- and phospho- peptides by el...

Ngày tải lên: 19/02/2014, 12:20

... in one of the German and English CELEX wordlists are automatically classified as such. This improved classifier results over tokens and types, as seen in Table 1 in the comparison of token and type precision ... comparison of D U , D T , log 10 f with ∆ log 10 f quency (log 10 f). D U = U w ˜ U w is defined as the ratio of the actual number of users of word w (U w ) over the ex...

Ngày tải lên: 19/02/2014, 19:20

Ngày tải lên: 20/02/2014, 18:20

... (Veltkamp and Tanase, 2000). Content-based indexing and re- trieval of images is based on features such as colour, texture, and shape. Yet, image understand- ing is not well advanced and is very ... "knife on table" vs. "blade on bar counter", and "cable around neck" vs. "neck with cable re- moved" respectively. SOCIS consists of a pipelin...

Ngày tải lên: 22/02/2014, 02:20