Báo cáo khoa học: Alternative splicing: regulation of HIV-1 multiplication as a target for therapeutic action docx
Báo cáo khoa học: Alternative splicing: regulation of HIV-1 multiplication as a target for therapeutic action docx
... hnRNP A1 C
UAGACUAGA 5428–5437
ESE2 SC35, SRp40 CCAGUAGAUCCUAGACUAGA 5418–5437
A5 ESE GAR ASF ⁄ SF2, SRp40 GAAGAAGCGGAGACAGCGACGAAGA 5558–5582 [7]
A7 ESS3 hnRNP A1 ,
hnRNP E1 ⁄ E2
AGAUCCAUUCGAUUAG
unknown
8047–8062 ... 32]
ISS hnRNP A1 UAGUGAAUAGAGUUAGGCAGGGA 7928–7950
ESE3 ASF ⁄ SF2 GAAGAAGAA 8016–8025
hnRNP A1 UAGAAGAAGAA 8018–8025
HIV-1 alternative splicing regulation J. Tazi e...
Báo cáo khoa học: Alternative splicing: role of pseudoexons in human disease and potential therapeutic strategies pot
... concentrations. N Engl J
Med 331, 974–980.
88 Faa
`
V, Incani F, Meloni A, Corda D, Masala M,
Baffico AM, Seia M, Cao A & Rosatelli MC. (2009).
Characterization of a disease-associated mutation affect-
ing ... JP, Markham AF, Giardina PJ, Li A &
Kazazian HH Jr. (1984) Beta-thalassemia in Chinese:
use of in vivo RNA analysis and oligonucleotide
hybridization in systematic cha...
Báo cáo khoa học: Alternative splicing: good and bad effects of translationally silent substitutions pdf
... altered isoform
proportions, activation of a control mechanism such as
nonsense-mediated decay, as well as the creation or
loss of splicing variants. As this process has a signifi-
cant impact on ... codon information, for an amino acid.
Translationally silent variations that
affect splicing and disease
Clinical studies identifying aberrant splicing mutations
are of great i...
Báo cáo khoa học: Alternative splicing produces an H-protein with better substrate properties for the P-protein of glycine decarboxylase doc
... (1988)
Resolution and characterization of the glycine cleavage
reaction in pea leaf mitochondria. Properties of the
forward reaction catalysed by glycine decarboxylase
and serine hydroxymethyltransferase. ... Germany). For exact
determination of the mean mass, the protein sample was
mixed with an aliquot of protein standard I (Bruker
Daltonics) to allow internal calibration, resulti...
Tài liệu Báo cáo khoa học: miRNAs and regulation of cell signaling pptx
... UGUUGUUUUAGUGAUCAGAAGGU
GY-box family miRNA
Brd-box: 5´ AGCUUUA
|||||||
dme-miR-4 3´ AGUUACCAACAGAUCGAAAUA
dme-miR-79 3´ UACGAACCAUUAGAUCGAAAUA
Brd-box family miRNAs
K-box: 5´ cUGUGAUa
||||||
dme-miR- 2a ... target mRNAs in a sequence-specific manner. A large number
of genes appear to be the target of miRNAs, and an essential role for
miRNAs in the regulation of various co...
Tài liệu Báo cáo khoa học: Small molecule regulation of Sir2 protein deacetylases ppt
... that an increase in Nmnat1 activity leads to
Fig. 2. (A) NAD
+
salvage pathway in yeast. (B) NAD
+
salvage pathway in mammals.
Small molecule regulation of Sir2 protein deacetylases O. Grubisha ... product formation [38,39]. Nicotin-
amide acts as a classical noncompetitive product inhi-
bitor of the forward deacetylation reaction and was
shown in vivo to decrease gene silencing, in...
Tài liệu Báo cáo khoa học: Oxygen-dependent regulation of hypoxia-inducible factors by prolyl and asparaginyl hydroxylation pdf
... asparagine in the CAD
wassubstitutedwithanasparticacidresidue,FIH-1
hydroxylase activity for the aspartic acid residue was only
7% of that obtained with asparagine. This clear difference
in amino ... other
asparaginyl hydroxylase enzymes, which can hydroxylate
both asparagine and aspartic acid residues, the FIH-1
enzyme was shown to have a clear preference for asparagine
in the CAD o...
Báo cáo khoa học: Calmodulin-mediated regulation of the epidermal growth factor receptor doc
... or
STIM2, acting as a Ca
2+
sensor, located in the ER
membrane, are translocated to the plasma membrane
and clustered at the ER-plasma membrane junctions
after the detection of a shortage of Ca
2+
in ... inositol-1,4,5-trisphosphate; Jak2, Janus kinase 2; JM, juxtamembrane; LD, like domain; NCX, Na
+
⁄ Ca
2+
exchanger; NLS,
nuclear localization sequence; PKC, protein kinase C; PMCA,...
Báo cáo khoa học: Alternative splicing: global insights potx
... Watahiki A, Nakamura M,
Arakawa T et al. (2003) Cap analysis gene expression
for high-throughput analysis of transcriptional starting
point and identification of promoter usage. Proc Natl
Acad ... [10] – as well
as a global analysis of alternative splicing changes pro-
duced as a result of splicing factor knockdown or
knockout, provide additional ‘factor-centric’ dataset...
Báo cáo khoa học: Characterization and regulation of a bacterial sugar phosphatase of the haloalkanoate dehalogenase ppt
... CTGCTGTAATAATGGGTAGAAGG
ARA439 GGAATTC
CATATGCGTATTATGGCCAG
ARA440 TATTTA
CTCGAGAATCCCCTCCTCAGC
ARA444 CG
GGATCCACCGTGAAAAAGAAAGAATTGTC
ARA451 GAATTCATAAAG
AAGCTTTGTCTGAAGC
ARA456 CGGCGCGT
CATATGGCCAGTCATGATA
ARA457 ... CGGCGCGT
CATATGGCCAGTCATGATA
ARA457 TGATACG
CATATGTCACCGGCTGGC
ARA458 CTCAGCCAATTTGGTTACATCCTTGTCCAAGTCAATCAGAATGCCAGCCGGTGCCAC
ARA459 GTGTCACCGGCTGGCATTCTGATTGACTTGGACAAGGATG...
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