Báo cáo khoa học: Human telomeric G-quadruplex: The current status of telomeric G-quadruplexes as therapeutic targets in human cancer pdf

... point out that there is an interesting proper subset of the infinite CFL's within which the human languages seem to fall. One further thing may be worth pointing out. The kind of string ... that could appear in the ~ and ~ strings, then the vocabulary of recursive nonterminals would have to be increased in proportion. (The second clause in the defini- tion...

Ngày tải lên: 24/03/2014, 01:21

... PDZ domain-containing proteins. The latter recognize a consen- sus s equence ( T/S-X-V/I) at the C-termini of membrane proteins [32]. Interaction of these PDZ-interacting motifs with PDZ domain-containing ... differently in canine cells. In the present work, we therefore used human MRP2 tagged with GFP at t he N-terminus, t hus leaving the C-terminus free for possible bindin...

Ngày tải lên: 31/03/2014, 09:20

... 1C). Increased nucleolin/C23 protein levels in Hsp70-transfected cells in response to H 2 O 2 -induced apoptosis We next examined the expression of nucleolin ⁄ C23 protein in these cells in response ... complexes with other factors, such as casein kinase II, c-Myb, midkine, histone H1, nucleophosmin, p53 and protein phosphatase 1. A number of studies, including our own, indica...

Ngày tải lên: 16/02/2014, 09:20

... immediately. Measurements of Mg 2+ -ATPase activity The inhibition of actomyosin-tropomyosin Mg 2+ -ATPase by the TnI-fragment and the release of the inhibition by TnC were measured in the presence of 0.05 ... to the regulatory TnC-binding site, from actin, resulting in the release of the inhibition and muscle contraction [17]. The structural TnC-bind- ing site...

Ngày tải lên: 20/02/2014, 01:20

... binary classifiers, each of which has been trained to match a specific type 1 Other binnings did not significantly alter the performance of the models we trained, and so we used the above binning strategy ... features As the foregoing implies, we are interested in train- ing a binary classifier, and so we represent each training and test instance in a feature space. Con- ceptual...

Ngày tải lên: 20/02/2014, 09:20

... Zn 2+ binding to the magnesium binding site M3 [4]. Fig. 4. The in uence of Mg 2+ on the kinetic properties of APase from E. coli. The in uence of Mg 2+ on the kinetic properties of APase from E. ... reduces the enzymatic activity indicating that binding of the last Zn 2+ ion, probably to the second M3 site, cannot supplement the role of magnesium in the ki...

Ngày tải lên: 21/02/2014, 00:20

... degradation Expression of an anticancer saporin chimera in the ER of Xenopus oocytes produced a drastic inhibition of translation in the RNA-injected cells [17]. Injection of neutralizing saporin antibodies in the ... dimethylsulfoxide in toxin-free media (Fig. 2). The cells were then incubated for another 16 h in the absence of saporin and dimethylsulfoxide befo...

Ngày tải lên: 07/03/2014, 05:20

... text. A.200 A.400 A.600 A.800 A.1000 A.1200 A.1400 0.86 0.88 0.90 0.92 0.94 B.200 B.400 B.600 B.800 B.1000 B.1200 B.1400 0.86 0.88 0.90 0.92 0.94 0.86 0.88 0.90 0.92 0.94 F C.200 C.400 C.600 C.800 C.1000 C.1200 C.1400 0.86 0.88 0.90 0.92 0.94 0.86 0.88 0.90 0.92 0.94 F Figure 6: The graph of micro-average F -measure against the number of training sentences during text chunking (A: MHH...

Ngày tải lên: 08/03/2014, 02:21

... from decreasing immigration to a steadily increasing im- migration trend, most of the graphic focuses on the decades of increasing immigration and the caption strengthens increasing trend in immigration ... that emphasizes the change in trend with a probability of 15.3%. However, when the verb increasing from the caption is taken into account, the probability of incr...

Ngày tải lên: 08/03/2014, 04:22

... a reappearance of the 145 kDa form on the cell surface, fol- lowing processing of the endoplasmic reticulum-associated pool of the 130 kDa form. Selective internalization of the 145 kDa form of the receptor ... studying guanylyl cyclase C (GC-C), the receptor for the guanylin/uroguanylin family of peptides. GC-C is predominantly expressed in intestinal cells, whe...

Ngày tải lên: 08/03/2014, 08:20