Báo cáo khoa học: How a lipid mediates tumour suppression Delivered on 29 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden pdf
Báo cáo khoa học: How a lipid mediates tumour suppression Delivered on 29 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden pdf
... 2010 The Author Journal compilation ª 2010 FEBS THE SIR HANS KREBS LECTURE How a lipid mediates tumour suppression Delivered on 29 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden Harald ... entail activation of autophagy, a catabolic pathway that is considered to mediate tumour suppression by scavenging damaged organ- elles that...
Ngày tải lên: 06/03/2014, 01:23
Báo cáo khoa học: Wisely chosen paths – regulation of rRNA synthesis Delivered on 30 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden potx
... mechanisms that control the chromatin structure and transcriptional activity of rRNA genes, in particu- lar the role of noncoding RNA in DNA methylation and transcriptional silencing. Abbreviations AMPK, ... dur- ing the last two decades has shown that regulation of rDNA transcription is manifested by multiple pathways that either act synergistically or operate in parallel. The...
Ngày tải lên: 29/03/2014, 21:20
Báo cáo khoa học: A decade of Cdc14 – a personal perspective Delivered on 9 July 2007 at the 32nd FEBS Congress in Vienna, Austria pdf
... CDK inactivation A question that arises from the observation that at least two pathways control Cdc14 localization is why budding yeast utilizes two pathways rather than one to regulate Cdc14? One ... the metaphase–anaphase transition, Separ- ase, a protease that triggers the separation of sister chromatids at the metaphase–anaphase transition [46] also regulates cyclin degrad...
Ngày tải lên: 23/03/2014, 06:20
Báo cáo khoa học: Pharmacology of vascular endothelium Delivered on 27 June 2004 at the 29th FEBS Congress in Warsaw pptx
... should have been. At the time, Bk was per- ceived as a mediator of pain and in ammation respon- sible for paralytic vasodilatation in the course of acute pancreatitis. The reasoning was as follows: ... PGI 2 - dependent mechanism [79]. In cultured bovine aortic endothelial cells lipophylic statins, i.e. atorvastatin, simvastatin and lovastatin (but not a hydrophilic pravastat...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: The yeast stress response Role of the Yap family of b-ZIP transcription factors The PABMB Lecture delivered on 30 June 2004 at the 29th FEBS Congress in Warsaw potx
... transcription factors in mediating the stress response. This is further substantiated by computational interactome data that predict their interaction [63]. Interestingly, the observation that Yap4 and ... Kluveromyces lactis contain a unique transcription activation domain N-terminal to the DBD [4,5]. The HSF is a pre-existing transcription activator that binds to an array of...
Ngày tải lên: 30/03/2014, 16:20
Báo cáo khoa học: Diversity of human U2AF splicing factors Based on the EMBO Lecture delivered on 7 July 2005 at the 30th FEBS Congress in Budapest pptx
... domains in each protein are aligned with U2AF 35 , and the similarity (% identity) of these domains in relation to U2AF 35 is indicated. Table 2. Domain organization of U2AF 35 and U2AF 35 -related proteins. ... (A) The putative functional domains in each protein are aligned with U2AF 65 , and the similarity (% identity) of these domains in relation to U2AF 65 is indicated. (B)...
Ngày tải lên: 23/03/2014, 10:20
Báo cáo khoa học: Mitochondrial calcium signalling in cell death Delivered on 1 July 2004 at the 29th FEBS Congress in Warsaw pptx
... regulation of aerobic metabolism and the induction of cell death, and new insight into the regulatory mechanisms operating in vivo. Abbreviations AGC, aspartate ⁄ glutamate metabolite carrier; ... truncated mutants lacking the Ca 2+ -binding domain [33]. Substantial evidence has built up in recent years indicating that metabolic regulation is only one of the roles of the mitocho...
Ngày tải lên: 30/03/2014, 20:20
Báo cáo khoa học: Hematopoietic differentiation from human ESCs as a model for developmental studies and future clinical translations Invited review following the FEBS Anniversary Prize received on 5 July 2009 at the 34th FEBS Congress in Prague docx
... showed that the p53 pathway acts not only as a tumor suppressor, but also sup- presses iPSC generation as determined using small interfering RNA and p53 mutation [89]. These findings indicate the ... studies have indi- cated that the placenta acts as an additional extrame- dullary hematopoietic organ during embryonic and fetal development [52,53]. Hematopoietic precursors found in t...
Ngày tải lên: 22/03/2014, 17:20
Báo cáo khoa học: Pyruvate:ferredoxin oxidoreductase and bifunctional aldehyde–alcohol dehydrogenase are essential for energy metabolism under oxidative stress in Entamoeba histolytica pdf
... present during the incubation (data not shown). As Cat only partially prevented enzyme inactivation, EhPFOR inactivation by H 2 O 2 was examined in detail. The enzyme was strongly inhibited in a dose-dependent manner ... DaPFOR, which is naturally resistant to inactivation under aero- bic conditions, contains an extra domain at the C-ter- minal region that spans the vicinal su...
Ngày tải lên: 15/03/2014, 23:20
Báo cáo khoa học: Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling Delivered on 24 October 2002 at the 28th FEBS Meeting in Istanbul potx
... within the ERK activation loop TEY motif is sufficient for total kinase inactivation [39], numer- ous phosphatases could be implicated in the two phases of inactivation: the rapid initial phase and ... cooperate to confer strong and specific binding for each MAPK-interacting molecules [28 ,29] . The spacing and organization of these different motifs on the different MAPK interacting...
Ngày tải lên: 31/03/2014, 07:20