Báo cáo khoa học: Structural evidence of a-aminoacylated lipoproteins of Staphylococcus aureus pot

... authors. Triacylated lipoproteins in S. aureus M. Asanuma et al. 728 FEBS Journal 278 (2011) 716–728 ª 2011 The Authors Journal compilation ª 2011 FEBS Structural evidence of a-aminoacylated lipoproteins of Staphylococcus ... 1420 1409.04 C49 C51 C52 C53 C48 C50 C55 Fig. 3. Triacylated structures of N-terminal peptides of SitC of other three S. aureus strains. MALDI-...

Ngày tải lên: 06/03/2014, 01:20

... development of lung fibrosis. One of the characteristics of pancreatic cancer is the overproduction of extracellular matrix by interstitial cells. This results in a tumour mass usually consisting of 60–80% ... cell infiltrates of the lung and fibro- sis in the liver [110]. Conclusions The novel members, PDGF-C and -D, of the PDGF subfamily of the cystine knot family of growth f...

Ngày tải lên: 19/02/2014, 07:20

... incubation of 2 lg of pure c 11 with 2 lgofc 1 purified in detergent, the slower migrating band reappeared (lanes 4 and 8). Upon incubation of 2 lg of pure c 11 with 2 and 10 lgofc 1 purified in chloroform ... state of the cells [18]. However, to date, no structural methods have been applied to clarify whether the stoichiometry of the c rings is influenced by variation of the exp...

Ngày tải lên: 07/03/2014, 21:20

... rapid degradation of the polysaccharide [33]. Detailed analy- sis of the putative CBM of BsArb43B does not show any evidence of extra sugar binding sites. However, determination of the surface charge ... has the b-propeller fold that is characteristic of this type of enzymes. Superposition of the Ca trace of the BsArb43B D. de Sanctis et al. Role of calcium in the glycos...

Ngày tải lên: 15/03/2014, 23:20

... 117 of PAL and makes a hydrogen bond to O3 of GlcNAc (Fig. 8A). Binding of GlcNAc in the )1 subsite of PAL is energetically favorable and contri- butes significantly to the higher affinity of PAL ... site of subunit A, but adopts an a ⁄ b mix- ture in the binding site of subunit B. Accommodation of the b-configuration in the binding site of PAL requires a change in the rotamer...

Ngày tải lên: 23/03/2014, 11:20

... expression of the propep- tide in leukocytes, and the structure, antimicrobial activity, and mechanism of action of the mature peptide were investigated. The proform is stored as a dimeric precursor of ... inactivation of S. aureus is slower than that of E. coli, which may be due either to a greater barrier effect of the thick extracellular peptidoglycan or to the particular m...

Ngày tải lên: 30/03/2014, 20:20

... γ) Φ(E[c(z)] + V γ) (8) where Φ(x) is the exponential of the first derivative of the log-gamma function. The optimal setting of π for the proportion of con- tent topics in the documents is empirically ... Journal of Machine Learning Research, 3(2-3):993 – 1022. H. Chen, SRK Branavan, R. Barzilay, and D.R. Karger. 2009. Global models of document structure using la- tent permutations...

Ngày tải lên: 30/03/2014, 21:20

... affinity of the C1 and C2 extracellular domains. Expression of C1 led to the apparent seques- tration of BMP-like ligands, resulting in the produc- tion of dorsalized phenotypes. Injection of relatively high ... major group of bilaterian animals, have remained in the background of the molecular survey of metazoan development. We report the cloning and functional study of the...

Ngày tải lên: 07/03/2014, 21:20

... structure of TenA. (A) Amino acid sequence of HP-TenA. The beginning and end of secondary structure elements of HP-TenA are shown in the bottom line. (B) Stereo view of a cartoon representation of the ... reminis- cent of that of human heme oxygenase-1 [13]. In the present study, we present the crystal structure of the HP1287 gene product as well as one of its mutants (F47...

Ngày tải lên: 16/03/2014, 00:20

... quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72, 248–254. 28 Page R & Stevens RC (2004) Crystallization data min- ing in structural ... K m ) of PRTFDC1 towards hypoxanthine and guanine was only 0.26% and 0.09%, respectively, of that of HPRT. This low activity could be explained by the fact that PRTFDC1 has a Gl...

Ngày tải lên: 15/02/2014, 01:20