... application of SH2 domain binding peptides, which results in blocking of the binding of the SH2 domain to the substrate and thereby preventing interaction of the substrate with the kinase domain. For ... Y527FD1)250N-terminal, SH3, SH2, kinase domain and C-terminusDeletion of N-terminal, SH3 and SH2 domain of kinase- dead n -Src B. R. Groveman et al. A novel function of Src SH2 and SH3 domains FEBS Journal ... cellular Src (c -Src) and neuronal Src (n -Src) , are found in neurons. n -Src contains a sixamino acid insertion in the SH3 domain, and is onlyexpressed in neurons [3]. The SH3 and SH2 domains in Src...