Báo cáo khoa học: Lysophosphatidylcholine modulates fibril formation of amyloid beta peptide doc

... Lysophosphatidylcholine modulates fibril formation of amyloid beta peptide Abdullah Md. Sheikh and Atsushi Nagai Department of Laboratory Medicine, Shimane University School of Medicine, ... of transmembrane amyloid precursor protein [1]. Bio- chemical analysis of the Ab peptides isolated from AD Keywords Alzheimer’s disease; amyloid beta peptide; fibril fo...

Ngày tải lên: 06/03/2014, 01:20

... fibril formation of piscine transthyretin: the role of the N-terminal. Mol Cell Endocrinol 295(1-2), 48–58. 34 Santos SD, Costa R, Teixeira PF, Gottesman M, Cardoso I & Saraiva MJ (2008) Amyloidogenic properties ... Stability and fibril formation of TTR and TRP FEBS Journal 276 (2009) 1999–2011 ª 2009 The Authors Journal compilation ª 2009 FEBS 2011 Stability and fibril...

Ngày tải lên: 16/03/2014, 01:20

... Mg 2+ - dependent influx. High copy number expression of Lpe10p led to an increased rate of uptake of Mg 2+ upon addition of 1 and 3 mm [Mg 2+ ] e . Expression of Mrs2–Lpe10p or Lpe10–Mrs2p chimeric proteins ... coexpression of Mrs2p-Myc (Fig. 6B, upper picture). Incubation of the same blot with anti-myc serum resulted in identification of Mrs2p-Myc-contain- ing complexes of h...

Ngày tải lên: 29/03/2014, 21:20

... dependence of the structural stabilities of FPs. (A) Inte- grated intensities of long-range NOE peaks of FP1. (B) Integrated intensities of short- and medium-range NOE peaks of FP1. (C) Frac- tions of ... solvent. Mode of formation of loosely packed structure through intermolecular interactions When the hydrophobic peptide fragment of FIV- VALG was added to the C-termi...

Ngày tải lên: 29/03/2014, 23:20

... transfer of phosphate esterified in the 5¢ position of 6-hydroxypu- rine monophosphate nucleosides [1]. The transfer of phosphate can lead to phosphorylation of inosine, guanosine and a number of their ... for the survival of several cell types. cN-II catalyses both the hydrolysis of nucleotides and transfer of their phosphate moiety to a nucleoside acceptor through formation...

Ngày tải lên: 15/02/2014, 01:20

... sub- unit of PP2A as modeled by comparison with the U2A¢–U2B¢¢ complex. The other two subunits shield most of the surface of PP2A–C. (B) Structure of the U2A¢–U2B¢¢ complex [20]. Study of the interactions ... The identification of phosphorylation sites of pp32 and bio- chemical purification of a cellular pp32-kinase. Biochem- istry 43, 10157–10165. 27 Bairoch A (1992) PROSITE: a...

Ngày tải lên: 18/02/2014, 17:20

... rate of transformation of S 1 into S 3 is calculated as corresponding to both the rate of consumption of S 1 , v(s 1 ), and the rate of production of S 3 , v(s 3 ), and the shape of the curves ... here. Results Kinetics of the overall reaction of transformation of S 1 into S 3 The system with only the free enzymes, E 1 and E 2 The overall rate of functioning of two fre...

Ngày tải lên: 19/02/2014, 06:20

... set of sequences of all superfamily members. To also visualise the more general relationships of the families included in MAPEG an unrooted consensus tree was produced. The consensus sequences of ... (1996) Sequence analysis of the gen- ome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of pote...

Ngày tải lên: 19/02/2014, 17:20

... native speakers of Arabic annotated 2855 sentences from Part 1 V 3.0 of the PATB. The sentences make up the first 400 documents of that part of PATB amounting to a total of 54.5% of the PATB Part ... contacting the first author. 587 of a sentence is judged as the objective reporting of information, it was labeled as OBJ. Otherwise, a sentence would be a candidate for one of th...

Ngày tải lên: 20/02/2014, 05:20

... composed of features like POS, the number of complements, category of each complement, and the position of comple- ments. In their view, structural disambiguation is simply another type of lexical ... adequate account of recur- sive syntactic structure is an essential component of any model of the behaviour. In this study, we tested a bigram POS tagger on different types of...

Ngày tải lên: 20/02/2014, 11:21