DO NOT DELAY: BREAST CANCER AND TIME, 1900-1970 pdf

... for both pre and post intervention measurements and for the affected and unaffected hands page116 [...]... method of measuring hand size in patients with breast cancer- related ... (World Cancer Research Fund 2013) Breast cancer in Scotland has increased by 13.7% since 2001 to a level that 29.4% of all women diagnosed with cancer in 2011 had breast cancer ... Borthwick, Yolande G (2014) The r...

Ngày tải lên: 22/12/2014, 21:42

... Canadian Partnership Against Cancer (2012) Cancer control snapshot: Second-hand smoke and cancer http://www.cancerview ca/idc/groups/public/documents/webcontent/crc snapshot pdf Accessed 28.03.14 Cassell, ... urgent need for adolescent girls to know about this new evidence, and for adolescent girls and boys who smoke to understand how their smoking puts their female peers at risk for breast c...

Ngày tải lên: 01/11/2022, 08:55

... participation of women in breast cancer screening tests [5], delayed helpseeking for breast cancer symptoms and barriers to accessing health care services [6] Breast cancer total delay is defined in ... of a questionnaire for estimation of breast cancer delay and its correlated factors It is a valid, reliable and sensitive instrument Keywords: Breast cancer, Delayed medical care, Questionnair...

Ngày tải lên: 05/11/2020, 08:13

... contributed details to the characterization of breast cancer subtypes Luminal A and luminal B breast cancers express the oestrogen receptor (ER) and are also frequently progesterone receptor (PR) ... HER2-overexpressing and luminal B subtypes, whereas triple-negative breast cancers are defined by lack of ER, PR and ERBB2 amplification [11-13] We have previously addressed mode of breast cancer...

Ngày tải lên: 05/11/2020, 06:56

... International Breast Cancer Conference suggested a surrogate definition of intrinsic subtypes of breast cancer: luminal A (ER + and/or PR+, Ki67 low and HER2-), luminal B (ER + and/or PR+, Ki67 high and/ ... International Breast Cancer Conference 2011 [10]: luminal A (ER + and/or PR+, Ki67 low and HER2-), luminal B (ER + and/or PR+, Ki67 high and/or HER2+), HER2-positive (ER-, PR- and HER2+)...

Ngày tải lên: 05/11/2020, 05:39

... regulatory mechanisms in breast cancer, whose activity determines the down-stream gene status of p16INK4a and cyclin D1, and consequently impacts the biologic behavior of breast cancer Methods Ethics ... biology Up to 70% of breast cancers show ERα expression, and two-thirds of ERα-positive breast carcinoma patients respond to treatment with anti-estrogen therapy [2-4], while breast cancer la...

Ngày tải lên: 05/11/2020, 01:21

... with breast cancer clinical outcome depend on the molecular subtypes Clin Cancer Res 2008, 14(16):5158 Drier Y, Domany E: Do Two Machine-Learning Based Prognostic Signatures for Breast Cancer ... and HER2-positive breast cancers Breast Cancer Res 2009, 11(2):R15 Teschendorff AE, Caldas C: A robust classifier of high predictive value to identify good prognosis patients in ER-negative breast .....

Ngày tải lên: 05/11/2020, 00:52

... and prostate cancer is known Estrogens and androgens act through their receptors by a direct transcriptional regulation of genes involved in cell growth and survival [4] In breast cancer, more ... PI3K-mTor, Erk1/2, TNBC (triple negative breast cancer), Kinase Inhibitors, AR (Androgen Receptor) Background The understanding of the heterogeneity of cancer is of great importance for the developm...

Ngày tải lên: 05/11/2020, 00:15

... significance of signal transducer and activator of transcription activation in breast cancer Clin Cancer Res 2002, 8(10):3065–3074 DeNardo DG, Coussens LM: Inflammation and breast cancer Balancing immune ... in breast cancer epithelial cells compared with FOXP3-positive T cells Clin Breast Cancer 2013, 13(4):264–270 Pardoll DM: The blockade of immune checkpoints in cancer immunotherapy Nat Re...

Ngày tải lên: 05/11/2020, 00:03

... IL-6 and IL-8 in freshly isolated BCSCs and benign SC (Figure 6) and compared to gene expression data Breast cancer cell lines MCF7 and T47D were used as positive controls for ERα, ERβ, and PR, and ... CRL-10317) and breast cancer cell lines, MCF7 (ATCC, HTB-22), T47D (ATCC, HTB-133) and HCC1806 (ATCC, CRL-2335) were authenticated by ATCC and confirmed through morphological examination and gr...

Ngày tải lên: 14/10/2020, 16:20

... the mechanisms underlying breast cancer etiology The Breast Cancer and Exercise Trial in Alberta (BETA) - a follow-up study to the Alberta Physical Activity and Breast Cancer Prevention (ALPHA) ... lifetime probability of developing breast cancer [1] and in the U.S this estimate is 1-in-8 [2] Inadequate physical activity is a probable risk factor for postmenopausal breast cancer [3] and ... m...

Ngày tải lên: 14/10/2020, 13:24

... density and morphology were judged on MGG stained slides and on ESL slides using DAPI nuclear staining Gb3 extraction from normal tissue, breast cancer specimens and HBCx Tumors and healthy breast ... N, Andrulis IL, Brenner DM, Clemons MJ: Changes in estrogen receptor, progesterone receptor and Her-2/neu status with time: discordance rates between primary and metastatic breast cancer Antican...

Ngày tải lên: 14/10/2020, 13:23

... BMC Cancer (2015) 15:53 DOI 10.1186/s12885-015-1059-6 RESEARCH ARTICLE Open Access Co-expression of S100A14 and S100A16 correlates with a poor prognosis in human breast cancer and promotes cancer ... subcellular localization and function of these molecules was examined by using the human breast cancer cell lines MCF7 and SK-BR-3, both of which highly express S100A14 and S100A16 proteins Cells...

Ngày tải lên: 30/09/2020, 13:47

... et al BMC Cancer 2014, 14:991 http://www.biomedcentral.com/1471-2407/14/991 RESEARCH ARTICLE Open Access Impact of breast cancer stage, time from diagnosis and chemotherapy on plasma and cellular ... with the biological activity and the overall burden of cancer TG reflects the procoagulant properties of both breast cancer and chemotherapy in the initial period of cancer diagnosis Thus the wei...

Ngày tải lên: 30/09/2020, 13:32

... Fernández Madrid et al BMC Cancer (2015) 15:407 DOI 10.1186/s12885-015-1385-8 RESEARCH ARTICLE Open Access Autoantibodies in breast cancer sera are not epiphenomena and may participate in carcinogenesis ... pre-malignant phase and that future studies using validated autoantibody panels may allow detection of breast cancer risk in asymptomatic women Autoantibodies developing in breast cancer a...

Ngày tải lên: 30/09/2020, 10:51