Báo cáo khoa học: Architecture of the Helicobacter pylori Cag-type IV secretion system pdf

... proteins. Other components are essential for the formation of the T4SS complex: VirB1 allows for the insertion of the system in the periplasm and VirB3, the function of which is unknown, is often associated ... has proved instru- mental in the production of genetically modified plants [7]. The second group of T4SS, exemplified by the ComB system of H. pylori...

Ngày tải lên: 06/03/2014, 00:21

... peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nat Immunol 5, 1166–1174. 6 Backert S & Selbach M (2008) Role of type IV secretion in Helicobacter pylori pathogenesis. ... by Helicobacter pylori. Trends Microbiol 18, 479–486. 10 Rohde M, Pu ¨ ls J, Buhrdorf R, Fischer W & Haas R (2003) A novel sheathed surface organelle of the Helic...

Ngày tải lên: 14/02/2014, 19:20

... Department of Psychotraumatology of the University of Heidelberg (Germany) assembled a comprehen- sive list of 400 qualified psychotherapists offering immediate support nationwide when needed. These ... particular those of group III, are effective against both Gram-positive and Gram-negative organisms. They further display excellent activity against Enterobacte- riaceae, the ent...

Ngày tải lên: 25/10/2012, 10:41

... dis- tribution of the height of the projection of the embed- ded molecule above the flat membrane surface, the average height was 5.4 ± 0.8 nm, which is in good agreement with the height of the cytoplasmic ... Histograms of the height differences between the top of SERCA and the surface of the membrane. Statistical section analy- ses of SERCA were performe...

Ngày tải lên: 14/02/2014, 14:20

... overexpression or activation in the brain might be beneficial for the treatment of neurodegenera- tive diseases, in particular AD: this progressive disor- der of the brain goes ahead with the loss of synaptic junctions ... [110]. These results are of special interest because the neuropeptide PACAP offers the opportunity of locally activating the PAC1 receptor and a-secr...

Ngày tải lên: 16/02/2014, 09:20

... preferentially the phosphorylation of the p46 isoform of JNK, whereas sorbitol treatment induced phosphorylation of both the p46 and p55 isoforms. To confirm functional activation of the JNK signaling ... phosphatase activity in the absence of myristoylation, the subcellular localization of the enzyme was altered. Compared with the wild type, the ability of nonm...

Ngày tải lên: 16/02/2014, 14:20

... preferences concerning the architecture of the HSEs [23,25]. The precise composition of an HSE can also determine the state of activation required of a specific HSF to induce transcription of its target ... has remained elusive. Nevertheless, in the light of current knowledge, most of the phosphory- lation events seem to repress the transactivation capac- ity of...

Ngày tải lên: 18/02/2014, 04:20

... 5875 Comparison of NMR spectra of SAIL and UL At3g16450.1 Although the concentration of the SAIL protein was lower than that of the UL protein by a factor of three (SAIL, 0.2 mm; UL, 0.6 mm), the NMR ... values for the N- and C-terminal domains versus the agglutinin are 2.2 and 2.0A ˚ , respec- tively. Thus each of the two domains of At3g16450.1 adopts a lectin fol...

Ngày tải lên: 18/02/2014, 14:20

... hydrolysis in the nucleotide-binding domain of the ABC transporter HlyB. EMBO J 24 , 1901–1910. 38 Kuhnke G, Neumann K, Mu ¨ hlenhoff U & Lill R (2006) Stimulation of the ATPase activity of the yeast ... inter- acts with the TOM receptor, responsible for the trans- location of the preproteins to the translocase of the inner mitochondrial membrane (TIM)23 comple...

Ngày tải lên: 18/02/2014, 16:20

... eggs in the one-cell stage to visualize the localization and to mea- sure the mobility of the components in the PGCs. The medaka embryo was peeled off the chorion, and the segment containing the ... G(τ) Relative intensity Fig. 3. FCS and FRAP analyses of Olvas–GFP in the PGC. FCS was used to measure the movement of Olvas–GFP into the cytosol out of the nuage...

Ngày tải lên: 18/02/2014, 16:20