Báo cáo khoa học: PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL pot

... overexpression suppresses endogenous LMO2 and HGAL expression Gene expression profiling previously performed by us [2] reveals that expression of HGAL and LMO2 is PRDM1 repression of LMO2 and HGAL ... repression of LMO2 and HGAL FEBS Journal 278 (2011) 3065–3075 ª 2011 The Authors Journal compilation ª 2011 FEBS 3075 PRDM1/Blimp1 downregulates expressio...

Ngày tải lên: 05/03/2014, 23:20

... model. Tables 3 and 4 show percentages of correct, in- correct and missing translations of personal and impersonal null subjects calculated on the basis of the number of personal and impersonal ... list of personal and impersonal verbs, and a part -of- speech tagging of the source docu- ment. We first present these two resources before describing the approach in more de...

Ngày tải lên: 24/03/2014, 03:20

... overexpression on steroidogenesis To further explore the role of MTE-I in the regulation of steroidogenesis, we examined the effect of MTE-I A B C Fig. 2. Effect of MTE-I knock down on steroidogenesis ... the involvement of ACS4 and MTE-I as important regula- tors in the mechanism of action of trophic hormone- stimulated cholesterol metabolism. To provide definitive proof about...

Ngày tải lên: 16/03/2014, 18:20

... Gilles Peltier 2 and Korne ´ l L. Kova ´ cs 1 1 Institute of Biophysics, Biological Research Center, Hungarian Academy of Sciences, and Department of Biotechnology, University of Szeged, Hungary 2 ... regula- tor remains unphosphorylated and binds to its target site and activates the expression of the hupSL (hoxKG and hoxFUYH) hydrogenase genes. In the absence of mol...

Ngày tải lên: 16/03/2014, 23:20

... available online: Fig. S1. Comparison of open reading frames of PrP and the splice variant of PrP (PrPSV) within exon 2 of PRNP in T98G cells. Fig. S2. Immunoblot analysis of recombinant human PrP and its splice variant. Fig. ... Alignment of amino acid sequences of plas- minogen activator inhibitor-1 and GPI ) PrPSV by FASTA searches. Table S1. Sequences of primers and...

Ngày tải lên: 30/03/2014, 04:20

... is a hand built self-contained lexicon: it con- sists of headwords and their definitions for the most familiar 28,000 words of Japanese. Each definition and example sentence has been parsed, and ... ontology. This makes it possible to test the use of similarity and/ or se- mantic class based back-offs for parsing and gen- eration with both symbolic grammars and statisti- cal mo...

Ngày tải lên: 20/02/2014, 12:20

... destina- tions and notices in transportation facilities, names of buildings and shops, explanations at sightseeing spots, and the names and prices of dishes in restau- rants. They are often written ... lot of wrong candidates. Fig- ure 2 shows a typical result of this OCR. Rectangles indicate erroneous candidates, even in background regions. On the other hand , as it identifies...

Ngày tải lên: 20/02/2014, 15:20

... loss of the axial water ligand. The corresponding spectral changes in the Soret band were therefore followed by stopped-flow and rapid-scan techniques, and the observed first-order rate constants of ... nature of the distal histidine residue in the autoxidation reaction of myoglobin and hemoglobin: Com- parison of the H64 mutants. Eur. J. Biochem. 267, 6166–6174. 4. Riggs, A. (1...

Ngày tải lên: 20/02/2014, 23:20

... other hand, fiction (F) and FL, a low-quality subset of F. For LPE, we defined a category D consisting of articles from quality broadsheets. Table 1 gives an overview of the categories and the ... frequencies were standardised using z-scores, so that the resulting random variables have a mean of 0 and a variance of 1. The z-scores were rounded 144 Proceedings of EACL...

Ngày tải lên: 22/02/2014, 03:20

... 855 MINIREVIEW Alternative splicing: role of pseudoexons in human disease and potential therapeutic strategies Ashish Dhir and Emanuele Buratti International Centre for Genetic Engineering and Biotechnology (ICGEB), ... cause of human disease is more frequent than previously thought. Here we aim to provide a review of the mechanisms that lead to pseudoexon activation in human gen...

Ngày tải lên: 06/03/2014, 09:22