Báo cáo khoa học: PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL pot

... overexpression suppresses endogenous LMO2 and HGAL expression Gene expression proﬁling previously performed by us[2] reveals that expression of HGAL and LMO2 isPRDM1 repression of LMO2 and HGAL ... repression of LMO2 and HGAL FEBS Journal 278 (2011) 3065–3075 ª 2011 The Authors Journal compilation ª 2011 FEBS 3075 PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL Elena ... lymphoma celllines downregulates endogenous mRNA and protein expression of both HGAL and LMO2. PRDM1 binds the HGAL and LMO2 promotersin vivoThe effect of PRDM1 on HGAL and LMO2 expres-sion...

Báo cáo khoa học: "Improving Machine Translation of Null Subjects in Italian and Spanish" pot

... model.Tables 3 and 4 show percentages of correct, in-correct and missing translations of personal and impersonal null subjects calculated on the basis of the number of personal and impersonal ... list of personal and impersonal verbs, and a part -of- speech tagging of the source docu-ment. We ﬁrst present these two resources beforedescribing the approach in more detail.List of personal and ... 4: Percentages of correct, incorrect and missing translation of zero-pronouns obtained by Moses. Averageis calculated on the basis of total pro-drop in corpus.translation. BLEU and similar MT...

Báo cáo khoa học: Silencing the expression of mitochondrial acyl-CoA thioesterase I and acyl-CoA synthetase 4 inhibits hormone-induced steroidogenesis potx

... overexpression on steroidogenesisTo further explore the role of MTE-I in the regulation of steroidogenesis, we examined the effect of MTE-IABCFig. 2. Effect of MTE-I knock down on steroidogenesis ... theinvolvement of ACS4 and MTE-I as important regula-tors in the mechanism of action of trophic hormone-stimulated cholesterol metabolism.To provide deﬁnitive proof about the role of MTE-I and ACS4 ... inMTE-I expression conﬁrms a previously expected role of MTE-I in the regulation of the rate-limiting step insteroidogenesis through the release of AA [12]. Consid-ering the crucial role of StAR...

Báo cáo khoa học: Hydrogen independent expression of hupSL genes in Thiocapsa roseopersicina BBS pot

... Gilles Peltier2 and Korne´l L. Kova´cs11 Institute of Biophysics, Biological Research Center, Hungarian Academy of Sciences, and Department of Biotechnology,University of Szeged, Hungary2 ... regula-tor remains unphosphorylated and binds to its targetsite and activates the expression of the hupSL (hoxKG and hoxFUYH) hydrogenase genes. In the absence of molecular hydrogen the kinase ... hup operon and expression of hupSL was reduced in a chromosomal hupR mutant, whichindicated that HupR was implicated in the activation process. The hupT and hupUV genes were isolated, and show...

Báo cáo khoa học: Hypoxia induces expression of a GPI-anchorless splice variant of the prion protein potx

... availableonline:Fig. S1. Comparison of open reading frames of PrP and the splice variant of PrP (PrPSV) within exon 2 of PRNP in T98G cells.Fig. S2. Immunoblot analysis of recombinant humanPrP and its splice variant.Fig. ... Alignment of amino acid sequences of plas-minogen activator inhibitor-1 and GPI)PrPSV byFASTA searches.Table S1. Sequences of primers and hydrolyzedprobes.Table S2. Expression of the splice ... brain and various tissues, including non-neuronal tissues [17], and, as discussed above, wedemonstrated constitutive expression of PrPSV mRNAFig. 4. Expression of the splice variant of PrP...

Tài liệu Báo cáo khoa học: "An Implemented Description of Japanese: The Lexeed Dictionary and the Hinoki Treebank" ppt

... is a hand built self-contained lexicon: it con-sists of headwords and their deﬁnitions for themost familiar 28,000 words of Japanese. Eachdeﬁnition and example sentence has been parsed, and ... ontology. This makesit possible to test the use of similarity and/ or se-mantic class based back-offs for parsing and gen-eration with both symbolic grammars and statisti-cal models.In order to make ... will look at ways of extending ourlexicon and ontology to less familiar words.2 The Lexeed Semantic Database of JapaneseThe Lexeed Semantic Database of Japanese con-sists of all Japanese words...

Tài liệu Báo cáo khoa học: "Portable Translator Capable of Recognizing Characters on Signboard and Menu Captured by Built-in Camera" docx

... destina-tions and notices in transportation facilities, names of buildings and shops, explanations at sightseeingspots, and the names and prices of dishes in restau-rants. They are often written ... lot of wrong candidates. Fig-ure 2 shows a typical result of this OCR. Rectanglesindicate erroneous candidates, even in backgroundregions. On the other hand , as it identiﬁes multiplecandidates ... use of a more robust OCR technologythat doesn’t ﬁrst extract character regions, by lan-guage processing to offset the OCR shortcomings, and by the use of the client-server architecture and the...

Tài liệu Báo cáo khoa học: The swinging movement of the distal histidine residue and the autoxidation reaction for midge larval hemoglobins docx

... loss of the axial water ligand. The correspondingspectral changes in the Soret band were therefore followedby stopped-ﬂow and rapid-scan techniques, and theobserved ﬁrst-order rate constants of ... nature of the distal histidine residue inthe autoxidation reaction of myoglobin and hemoglobin: Com-parison of the H64 mutants. Eur. J. Biochem. 267, 6166–6174.4. Riggs, A. (1981) Preparation of ... compared with those of another component Ta-V HbO2 and sperm whale MbO2, and described based on a nucleophilic displacement mech-anism. In light of the O2binding aﬃnity, Bohr eﬀect and considerable...

Tài liệu Báo cáo khoa học: "Exploring the Use of Linguistic Features in Domain and Genre Classification" potx

... other hand, fiction (F) and FL, a low-quality subset of F. For LPE, we defined a category D consisting of articles from quality broadsheets. Table 1 gives an overview of the categories and the ... frequencies were standardised using z-scores, so that the resulting random variables have a mean of 0 and a variance of 1. The z-scores were rounded 144 Proceedings of EACL '99 down ... frequent in texts from law and science, both of which tend to contain texts of argumentative types. The frequency of infini- tives of auxiliaries reflects both the use of passive voice, which...

Báo cáo khoa học: Alternative splicing: role of pseudoexons in human disease and potential therapeutic strategies pot

... 855MINIREVIEWAlternative splicing: role of pseudoexons in human disease and potential therapeutic strategiesAshish Dhir and Emanuele BurattiInternational Centre for Genetic Engineering and Biotechnology (ICGEB), ... cause of human disease is morefrequent than previously thought. Here we aim to provide a review of themechanisms that lead to pseudoexon activation in human genes and howthe various cis- and ... intronicsequences of most genes [with this term we refer toany nucleotide sequence between 50 and 200–300nucleotides in length with apparently viable 5¢ and 3¢splice sites (5¢ss and 3¢ss) at either...

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