Hydroxyurea for the Treatment of Sickle Cell Disease docx

... Labeling The current labeled dosing of hydroxyurea for sickle cell disease calls for the administration of an initial dose of 15 mg/kg/day in the form of a single dose, with monitoring of the patient’s ... development at the time of the review. We applied evidence grades to the bodies of evidence about the efficacy and/or effectiveness of hydro...

Ngày tải lên: 05/03/2014, 10:20

... stroke, in the children randomized to the transfusion arm. At the end of the trial, all participants were offered periodic transfusion therapy. The main side effects of the transfusion therapy were ... completely. Therefore, it is not recommended. The usual treatment for pediatric patients in the acute stage of ischemic stroke is hydration with transfusion, althoug...

Ngày tải lên: 21/02/2014, 12:20

... cost. There is no cure for AD, and the development of effective therapeutic strategies is hampered by a paucity of information on the biolo- gical mechanisms underlying the disease. The severity of ... have the potential to ameliorate several of the dysfunctional events characteristic of Alzheimer’s disease. Metal-based therapeutics have already provided promising re...

Ngày tải lên: 07/03/2014, 10:20

... from data in the RCT. The survival of patients receiving ASC/BSC was calculated from the survival of the patients in the cetuximab monotherapy arm of the RCT. The data from the monotherapy arm ... this situation, where no other active treatment was available, could prolong survival for a number of months if the disease responded to the drug. The Committ...

Ngày tải lên: 14/02/2014, 22:20

... investigated the efficacy of facet debridement for the treatment of facet joint pain. Summary of background data: Facet joint disease, often due to degenerative arthritis, is common cause of chronic ... considering the endoscopic option. The facet injections in these 72 patients gave 50 to 100% relief of their pain in 86% of the patients with a median relief per...

Ngày tải lên: 26/10/2012, 09:32

... laminoforaminoplasty for the treatment of thoracic radiculopathy: report of 12 cases Scott M.W. Haufe 1,2  , Ryan A. Baker 3 and Morgan L. Pyne 3 1. Chief of Pain Medicine and Anesthesiology ... quality of life. Conservative therapy is the initial treatment of choice, but fails to provide relief in a substantial number of patients. Central and foraminal sten...

Ngày tải lên: 26/10/2012, 09:57

... ethanol at a final concentration of 10%, then transported to the laboratory of UT at 4oCstored. Then, each of the samples were divided into two. One of them was for DNA extraction and was washed ... general, the higher concentration of primers can lead to the formation of primer dimers. Also, the cost of the chemicals should be minimized if the same quantitati...

Ngày tải lên: 05/09/2013, 09:38

... with the increased HRT of the adsorption tank. From an engineering application point of view, the appropriate operational parameters of the recycle ratio, HRT of the regeneration tank, HRT of the ... technical feasibility of this process was demonstrated. The effects of recycle ratio, HRT of the regeneration tank, HRT of the adsorption tank and SRT of...

Ngày tải lên: 05/09/2013, 09:38

... minimising the impact of disease. At least 30% of patients require surgery in the first 10 years of disease and approximately 70–80% will have surgery in their lifetime. 3.3 Other disease sites ≥ ... Guidelines for the Management of Inflammatory Bowel Disease (IBD) in Children in the United Kingdom 23 Guidelines for the Management of Inflammatory Bowel Disease...

Ngày tải lên: 12/02/2014, 11:20

... 15-20% of infants and young children with sickle cell anemia die before the age of 5, usually of septicemia or meningitis. In children under 6 years of age with sickle cell disease, the predominant ... Management of Sickle Cell Disease in Children. Page 3 of 15 Inclusion Criteria: • Sickle cell patients presenting with signs of VOC. • Presenting sig...

Ngày tải lên: 05/03/2014, 12:20