Tài liệu Báo cáo Y học: Presence and regulation of the endocannabinoid system in human dendritic cells potx

... the presence of the endocannabinoids, anandamide and 2-arachidonoylglycerol (2-AG), the cannabinoid CB 1 and CB 2 receptors, and one of the enzymes mostly responsible for endocannabinoid hydrolysis, ... from monocytes, and as monocytes were previously described to express the endocannabinoid system, we investigated the presence and regulation of endocann...

Ngày tải lên: 22/02/2014, 07:20

... results indicate that SPO14/PLD1 may be involved in regulating the expression of genes that are part of the INO1 regulon [13]. Therefore, we examined the effect of the presence of inositol and choline ... Characterization and regulation of yeast PtdEtn-PLD activity (Eur. J. Biochem. 269) 3823 in the presence of Ca 2+ we lysed the yeast cells in the...

Ngày tải lên: 22/02/2014, 07:20

... 36% of the interaction of the full peptide with the binding cavity of SM3. The sizes of the surfaces were determined using distances between ligand atoms and protein atoms of less than 3 A ˚ . These ... struc- ture into the binding cavity of SM3 and the binding epitope obtained from STD NMR is very good. Comparison with the X-ray and previous NMR structures A...

Ngày tải lên: 21/02/2014, 15:20

... coordination of the phosphorylation of UTP and hydrolysis of glutamine for optimal efficiency in CTP synthesis rather than just acting to increase the rate of glutamine hydrolysis itself. Keywords: ... activity, (B) CTP synthesis in the absence of GTP and (C) CTP synthesis in the presence of GTP. (A) Glutamine hydrolysis in the absence of nucleotides takes...

Ngày tải lên: 21/02/2014, 15:20

... between the se two classes. Role of Tyr183 in catalysis In previous crystallographic studies it was shown that the hydroxyl side chain of Tyr183 is within hydrogen bonding distance of the N-acetyl ... residue resulting from the cloning procedure has apparently been cleaved off during the maturation of the e nzyme. Enzyme activity studies The lysozyme activities of...

Ngày tải lên: 22/02/2014, 04:20

... the phenotype of cells [53]. Further- more, in human breast tumors and cell lines, miR-17- 5p and miR-20a are induced in a manner that depends on cyclin D1 and repress the expression of cyclin ... sig- naling pathway. Some other miRNAs are also reported to be induced by the MAPK signaling pathway. In the human B-cell line Ramos, miR-155 is induced by signaling by...

Ngày tải lên: 14/02/2014, 19:20

... behave differently from the rest of the promoters. Of these, amino acid residues 243 and 275 are involved in DNA binding and 244 and 246 are in very close proximity to DNA binding. This indi- cates ... either does not use these residues for binding or that they are not necessary for binding as the DNA binds sufficiently hard to the other DNA binding residues. For the WA...

Ngày tải lên: 18/02/2014, 11:20

... age of 8 years, the top of the frontal sinuses is at the level of the orbital roof, and by the age of 10 years, the sinuses extend into the vertical portion of the frontal bone. The final adult ... By the age of 4 years, the average cranial extent of the frontal sinus reaches half the height of the orbit and extends just above the top of...

Ngày tải lên: 25/10/2012, 11:04

... [6,7]. The methylation pattern is created by de novo methylation and demethyla- tion of the DNA, and maintained during mitosis by maintenance methylation [reviews 8,9]. De novo methyla- tion of DNA ... methyl groups are always introduced, one slowly by Dnmt3a or by de novo methylation catalyzed by Dnmt1 and the second one very fast. Therefore, this effect can only double the...

Ngày tải lên: 21/02/2014, 01:21

... results of the strand-break assay of yeast tRNA Phe in the presence of Ami, Cu(II)-Ami and the Cu(II)-Ami-H 2 O 2 system, performed by means of poly- acrylamide gel electrophoresis. Strikingly, in the ... to the linear form III. In the Cu(II) + H 2 O 2 system, the amount of form II increased during the duration of the experiment. Only for the comple...

Ngày tải lên: 21/02/2014, 01:21