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Tài liệu Alcohol-use disorders: diagnosis, assessment and management of harmful drinking and alcohol dependence docx

Tài liệu Alcohol-use disorders: diagnosis, assessment and management of harmful drinking and alcohol dependence docx

Tài liệu Alcohol-use disorders: diagnosis, assessment and management of harmful drinking and alcohol dependence docx

... be part of the routine care of all service users inspecialist alcohol services and should: Alcohol- use disorders: diagnosis, assessment and management of harmful drinking and alcohol dependence NICE ... withdrawalAPQ for the nature and extent of the problems arising from alcohol misuse. Alcohol- use disorders: diagnosis, assessment and management of harmful drinking and alcohol dependence NICE clinicalguideline ... persists after a period of abstinence ora significant reduction in alcohol intake. Alcohol- use disorders: diagnosis, assessment and management of harmful drinking and alcohol dependence NICE clinicalguideline...
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The management of harmful drinking and alcohol dependence in primary care potx

The management of harmful drinking and alcohol dependence in primary care potx

... INTERVENTIONS FOR HAZARDOUS AND HARMFUL DRINKING THE MANAGEMENT OF HARMFUL DRINKING AND ALCOHOL DEPENDENCE IN PRIMARY CARE101+1+In A&E departments where brief interventions are offered by busy ... NetworkThe management of harmful drinking and alcohol dependence in primary careA national clinical guideline1 Introduction 12 Detection and assessment 43 Brief interventions for hazardous and harmful ... experience of the guidelinedevelopment groupTHE MANAGEMENT OF HARMFUL DRINKING AND ALCOHOL DEPENDENCE IN PRIMARY CARE28Annex 1 Alcohol content of some beveragesBeverage type Alcohol by volume...
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Tài liệu Global Chemicals Outlook Towards Sound Management of Chemicals pptx

Tài liệu Global Chemicals Outlook Towards Sound Management of Chemicals pptx

... trends including costs of inaction and the benefits of action; and 3. Instruments and approaches for sound management of chemicals, including promotion of safer alternatives and guidance to accelerate ... prospects for widespread and multifaceted exposures of humans and the environment to chemicals of high and unknown concern also arise. Of the tens of thousands of chemicals on the market, ... occupational carcinogens and particulates and lead, correspond to a total of 964,000 deaths and 20,986,153 DALYs, corresponding to 1.6% of the total deaths and 1.4% of the total burden of disease worldwide.To...
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Tài liệu THE OLD MERCHANT MARINE, A CHRONICLE OF AMERICAN SHIPS AND SAILORS pptx

Tài liệu THE OLD MERCHANT MARINE, A CHRONICLE OF AMERICAN SHIPS AND SAILORS pptx

... Fishing-Trade, upon a mighty shelf of rock and banks of sand that lie where he had informed himself." CHAPTER II. THE PRIVATEERS OF '76 The wars of England with France and Spain spread turmoil ... "The Ships and Sailors of Old Salem: The Record of a Brilliant Era of American Achievement" (1912). A history of the most famous seaport of the Atlantic coast, drawn from log-books and other ... autobiographies of the old school of shipmasters who had the gift of writing. Captain Amasa Delano, "Narrative of Voyages and Travels" (1817). Another of the rare human documents of blue...
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Tài liệu SWIMMING IN SEWAGE: The Growing Problem of Sewage Pollution and How the Bush Administration Is Putting Our Health and Environment at Risk ppt

Tài liệu SWIMMING IN SEWAGE: The Growing Problem of Sewage Pollution and How the Bush Administration Is Putting Our Health and Environment at Risk ppt

... spawning, and breeding habitats to hundreds of species of birds, recreational and commercial fish and shellfish, and threatened and endangered species such as manatees, sea turtles, and Gulf ... intensity of sewage overflows and sewage treatment bypasses. The EPA’s Office of Research and Development is currently assessing the potential impacts of climate change on the frequency and size of ... 900,000 cases of illness and as many as 900 deaths as a result of waterborne microbial infections;137,138 and • 500,000 cases of illness per year attributed to microbial contamination of drinking...
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Tài liệu Báo cáo khoa học: Mitochondrial targeting of intact CYP2B1 and CYP2E1 and N-terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae ) role of protein kinase A in the mitochondrial targeting of CYP2E1 pdf

Tài liệu Báo cáo khoa học: Mitochondrial targeting of intact CYP2B1 and CYP2E1 and N-terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae ) role of protein kinase A in the mitochondrial targeting of CYP2E1 pdf

... determinations of the supernatant containing resorufin were made at the exci-tation and emission wavelengths of 528 nm and 590 nm,respectively. The ERND activities of mitochondria and mitoplast ... NADPH, and 4 mm NDMA in a 1.0 mL finalvolume. The reaction mixture was incubated at 37 °C for30 min, and the reaction was stopped by the addition of 0.1 mL of 25% zinc sulfate and 0.1 mL of saturated ... mitochondrialtargeting of CYP2E1Naresh B. V. Sepuri, Sanjay Yadav, Hindupur K. Anandatheerthavarada and Narayan G. AvadhaniDepartment of Animal Biology, School of Veterinary Medicine, University of Pennsylvania,...
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Tài liệu Báo cáo khoa học: Differential effects of Mxi1-SRa and Mxi1-SRb in Myc antagonism ppt

Tài liệu Báo cáo khoa học: Differential effects of Mxi1-SRa and Mxi1-SRb in Myc antagonism ppt

... differentiation, and so on. Isoforms of numerousproteins have been studied and compared in this man-ner, including alternative isoforms of members of thep53 ⁄ p63 ⁄ p73 [23] and the Bcl2 families ... versions of these twoisoforms, as well as of the Mxi1-WR isoform that lacksthe SID, and shown to give rise to proteins of theexpected size expressed at similar levels (Fig. 1A). Each of these ... theeffects of the PRD are context sensitive, and coulddepend on variables including cellular milieu and pro-moter environment. It is of interest in this regard that,in our hands, Mxi1-SRa and Mxi1-SRb...
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Tài liệu Báo cáo khoa học: Identification of b-amyrin and sophoradiol 24-hydroxylase by expressed sequence tag mining and functional expression assay docx

Tài liệu Báo cáo khoa học: Identification of b-amyrin and sophoradiol 24-hydroxylase by expressed sequence tag mining and functional expression assay docx

... suspen-ded in 25 mL of 40% potassium hydroxide and 25 mL of methanol and refluxed for 2 h. Products were extractedwith 50 mL of hexane. The hexane layer was washed with25 mL of saturated sodium ... range of structural diversity produced by asequence of biosynthetic reactions. Cyclization of oxidosqualene is the ini-tial origin of structural diversity of skeletons in their biosynthesis, and ... shown), none of hydroxylated triterpenes and their glycosides has been identified. The lack of understanding of triterpene metabolism in A. thalianamakes it difficult to identify the function of each...
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Tài liệu Báo cáo khoa học: Thermal unfolding of smooth muscle and nonmuscle tropomyosin a-homodimers with alternatively spliced exons docx

Tài liệu Báo cáo khoa học: Thermal unfolding of smooth muscle and nonmuscle tropomyosin a-homodimers with alternatively spliced exons docx

... comparison of Tm5a with smTm allows study of the effects of replacement of muscle exons 1a and 2a by nonmuscleexon 1b, and comparison of Tm5a with Tm5b allowsthe effects of exchange of exon 6 ... of Tm (a and b), each containing 284residues. Smooth and skeletal muscles express differ-ent isoforms resulting from alternative splicing of thea and b genes.There are two major classes of ... unfolding of homo- and het-erodimers of skeletal [15,16] and smooth [17–19]muscle Tm, their mutants [20–23], and numerouscoiled-coil model peptides corresponding to the N- and C-terminal parts of...
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Tài liệu Báo cáo khóa học: The effect of mutations surrounding and within the active site on the catalytic activity of ricin A chain pptx

Tài liệu Báo cáo khóa học: The effect of mutations surrounding and within the active site on the catalytic activity of ricin A chain pptx

... addition of 100 lLof2· Kirby buffer [25] and 80 lLofH2O, and rRNA was obtained by precipitation after two phenol–chloroform extractions. Four micrograms of rRNA weretreatedwith20lL of acetic-aniline ... Electron density of RTA R213D in the vicinity of residue 213. The backbone and sidechains of the R213D substitution are shown as stereoimages in thick ball and stick and the position of the Arg213 ... 234 and 235 [9]. Of theses residues, only Arg213 is in thevicinity of the active site of RTA. In order to establish therole of arginyl residues around the active site of RTA inthe binding of...
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