Tài liệu Báo cáo Y học: Convulxin induces platelet shape change through myosin light chain kinase and Rho kinase ppt

... Convulxin induces platelet shape change through myosin light chain kinase and Rho kinase Silvia Riondino, Pier P. Gazzaniga and Fabio M. Pulcinelli Department of Experimental Medicine and ... Ca 2+ concentration and shape change in Ó FEBS 2002 Convulxin- induced platelet shape change (Eur. J. Biochem. 269) 5879 convulxin- induced platelet activati...

Ngày tải lên: 21/02/2014, 01:21

... transition observed using DSC, and are sometimes accessible through X-ray crystallography. It has already been suggested b y Holt & Sawyer [3] that the open and relatively mobile con formation of ... are very similar to those of disordered poly( L - glutamic acid) at high pH and poly( L -lysine) at low pH [18,19]. Accordingly, the ROA spectra of disordered poly( L - lysine) and...

Ngày tải lên: 21/02/2014, 15:20

... gastric lipase, and endothelial lipase [1,2]. The primary function of LPL is triglyceride hydrolysis in triglyceride-rich lipoproteins, such as chylomicron and very low density lipoprotein (VLDL) ... with the MARKIT-F LPL kit, and chromatography fractions were analyzed by Western blotting with LPL polyclonal antibody 7640 (B). Fig. 2. Heparin affinity of wild-type and basic amino acid–s...

Ngày tải lên: 21/02/2014, 15:20

... chlorophyll; SQDG, sulfoquinovosyl diacylglycerol; MGDG, monogalactosyl diacylglycerol; DGDG, digalactosyl diacylglycerol; PtdG, phosphatidylglycerol; PSI, photo- system I; PSII, photosystem II; ... monogalactosyl diacylglycerol (MGDG), digalactosyl diacylglycerol (DGDG), phosphatidylglycerol (PtdG) and sulfoquinovosyl diacylglycerol (SQDG). The lipophilic matrix may promote the efficiency o...

Ngày tải lên: 22/02/2014, 04:20

... discontinuous gap- and step-type Two trimers on 4P-type HSE One trimer on step-type HSE One trimer on gap-type HSE One trimer on 3P-type HSE 4P type A B a b c d nTTCnnGAAnnTTCnnGAAn 3P type nTTCnnGAAnnTTCn Gap ... (3P-, gap-, or step-type). How- ever, the C-terminal modulator, and thereby hyper- phosphorylation, are not necessary for transcriptional activation by trimers cooperatively bou...

Ngày tải lên: 18/02/2014, 04:20

... oligomycin of L6 cells showed that they were very well coupled. The oligomycin resistant respiratory activity of the cells could be strongly stimulated by the addition of the protonophore carbonyl ... mitochondria and remained lean despite their hyperphagia. The properties of UCP2 and UCP3 overexpressed in yeast mitochondria have been recently questioned [24,25]. Careful analysis has show...

Ngày tải lên: 21/02/2014, 15:20

... c -chain and the tyrosine kinase Syk, which is tyrosine phosphorylated and activated early after GPVI engagement. Phosphorylation of FcR c -chain was assessed in K562 cells expressing FcR c -chain ... the cytoplasmic tail Fig. 6. Phosphorylation of FcR c-chainandSykinK562cells.(A) K562 cells stably expressing FcR c -chain (pRc/c), or cotransfected with either wild-type GPVI and Fc...

Ngày tải lên: 22/02/2014, 07:20

... 2002 conformational changes caused by the ligand are easily sensed by the P-pyridoxyl chromophore. Figure 4 shows the modeled structure of the P-pyridoxyl-PEP carboxykinase in the free and substrate ... phosphoryl and pyridoxyl moieties of the P-pyridoxyl group are shown in red and magenta, respectively. The fractional solvent exposed area of the P-pyridoxyl group is 0.39 and 0.082 fo...

Ngày tải lên: 21/02/2014, 01:21

... of methyl a- D -glucopyranoside (1a)andmethyla- D -manno- pyranoside (1c), methyl 6-deoxy-6-isothiocyanato-a- D - glucopyranoside (1e), b- D -glucopyranosyl isothiocyanate (3c)andb- D -glucopyranosyl ... Methyl 2,3-anhydro-a- D -allopyr- anoside (2a) and methyl 3,4-anhydro-a- D -galactopyrano- side (2b) were obtained by desilylation of 1 mmol of the 6-O-[dimethyl-(1,1,2-trimethylpropyl)sily...

Ngày tải lên: 21/02/2014, 01:21

... groups are always introduced, one slowly by Dnmt3a or by de novo methylation catalyzed by Dnmt1 and the second one very fast. Therefore, this effect can only double the rate of DNA methylation, because every ... in mammals during late embryogenesis [6,7]. The methylation pattern is created by de novo methylation and demethyla- tion of the DNA, and maintained during mitosis by maintenanc...

Ngày tải lên: 21/02/2014, 01:21