Tài liệu Báo cáo khoa học: Neuropeptide Y-family receptors Y6and Y7in chicken Cloning, pharmacological characterization, tissue distribution and conserved synteny with human chromosome region docx

... Y-family receptors Y 6 and Y 7 in chicken Cloning, pharmacological characterization, tissue distribution and conserved synteny with human chromosome region Torun Brome ´ e* ,1 , Paula Sjo ¨ din* ,1 , ... al. NPY-family receptors Y6 and Y7 in chicken FEBS Journal 273 (2006) 2048–2063 ª 2006 The Authors Journal compilation ª 2006 FEBS 2063 Neuropeptide Y...

Ngày tải lên: 19/02/2014, 07:20

... different receptors (Y1, Y2, Y4, Y5 and y6) that vary in their binding profiles and in their distribution in the central nervous system and periphery. Y1, Y2 and Y5 are the best characterized NPY receptors, ... Koshihara Y & Nagatsu T (1997) Expression of mRNAs for neuropeptide recep- tors and beta-adrenergic receptors in human osteoblasts and human osteogenic sarc...

Ngày tải lên: 18/02/2014, 04:20

... [19], and NMR spectroscopic data of p25a homologs from mice, Caenorhabditis elegans and humans [20–22] demon- strate a folded central core and unfolded N- and C-ter- minal extensions of  45 and ... 1. Determination of V max and K m for DAT, NET and SERT in the presence and absence of p25a. HEK-293-MSR cells were tran- siently transfected with DAT, NET or SERT and with p...

Ngày tải lên: 14/02/2014, 21:20

... incubated with the reactivase in the presence of ADP and Mg 2+ and followed by nondenaturing PAGE, the bands of the enzyme and the reactivase were markedly reduced in density, and two bands of ... c, e, and g). To determine their subunit compositions, bands i–vi were excised and subjected to SDS⁄ PAGE on 6% and 14% gels (Fig. 5B,C), followed by densito- metric analyses. Both b...

Ngày tải lên: 15/02/2014, 01:20

... which occur together with L858R [12]. Exon 19 deletional mutation and L858R result in increased and sustained phosphorylation of EGFR and other ERBB family proteins without ligand stimulation. It ... amphi- regulin and epigen); (b) those that bind to EGFR and ERBB4 (including betacellulin, heparin-binding EGF and epiregulin); and (c) neuregulin (NRG) (also known as heregulin)...

Ngày tải lên: 16/02/2014, 09:20

... enhan- cer regions of SV40 and human metallothionein IIA [1]. The AP-2 family of transcription factors is composed of five members: AP-2a, AP-2b, AP-2c, AP-2d, and AP-2e [2–7], described for humans and ... found in frogs and fish, and homologs occur in invertebrates. All AP-2s have a highly conserved basic helix–span–helix DNA-binding and dimerization domain at their C-terminus,...

Ngày tải lên: 16/02/2014, 09:20

... first conserved binding site, which then leads to the development of gastric adeno- carcinoma. Materials and methods Human cancer tissue samples Fresh-frozen human gastric adenocarcinoma tissue ... biological processes and may be important in tumorigenesis. In the analysis of miRNA expression differences in four pairs of gastric adenocarcinoma tissue samples and matched norma...

Ngày tải lên: 18/02/2014, 04:20

... pathways with in vitro cytosol and cell-free mitochondria, our data suggest a direct interaction between ETA and cyto- solic EF-2 on the one hand, and the mitochondrial membrane on the other hand. ... cathepsins B and D, with the major cleavages generated in vitro occurring mainly within domain III of ETA-A. Cell-free endosomes preloaded in vivo with ETA intraluminally processed...

Ngày tải lên: 18/02/2014, 04:20

... acid and a base on each side of the hydrolyzed bond [16]. E96 and H137 in a-sarcin and E58 and H92 in RNase T1 act as the base and acid groups, respectively. Com- paring the 3D structures, E66 and ... equipped with a triple-resonance cryo- probe and an active shielded z-gradient coil, or with a con- ventional TXI probe and x-, y- and z-gradients. Traditional 2D COSY, TOC...

Ngày tải lên: 18/02/2014, 08:20

... were injected with VgR–dsRNA1 and EGFP–dsRNA, and  150 pupae were injected with buffer only. Virgin queens at days 0 (the day of virgin queen emergence), 5 and 10 were collected, and the ovaries ... analyzed and images were obtained with an AxioCam MRc color camera (Carl Zeiss) and analyzed with axiovision (Carl Zeiss). RNAi A SiVgR clone was used as a template for the sy...

Ngày tải lên: 18/02/2014, 08:20