Tài liệu Báo cáo khoa học: Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines docx

... (C-terminal)- containing fragment ions. Thus, for the + 1.0 Da sam- ple (Fig. 8B), the N-terminal fragment ions show little increase in mass with increasing size until Asn67, with this increase of ... squares represent the distribution 1 Da higher. To determine the mass increase with increasing time of deamidation (pH 9.6), the best fit of calculated intensity values (s...

Ngày tải lên: 18/02/2014, 16:20

... that (a) the observed inhibition is lower than that with the theoretical inhibitor, regardless of the enzyme, the inhibitor and the state of oxidation of the latter, indi- cating that elastin does ... inhibition of Pr3 by the oxidized inhibitors. While the above data are in overall agreement with the results obtained using synthetic substrates, they also indi...

Ngày tải lên: 19/02/2014, 07:20

... was > 90–97%. To determine whether de novo protein synthesis was required for induction of S100A8 mRNA, confluent 3T3 cells were preincubated with the protein synthesis inhibitor, cycloheximide ... organization in vitro. J Cell Biochem 88, 848–854. 9 Ito M & Kizawa K (2001) Expression of calcium-bind- ing S100 proteins A4 and A6 in regions of the epithelial sac asso...

Ngày tải lên: 19/02/2014, 18:20

... binding play no (or a very minor) role in the hydrolysis of oligomeric substrates. The SBS is located too far from the active site to in uence the binding and catalysis of these substrates in ... engineering of the SBS of XBS, the results obtained in the previous screening experiment directly Table 1. The effect of genetic engineering of the secondary bi...

Ngày tải lên: 14/02/2014, 19:20

... attack of the L-hOrn 3 a-amino group onto l-haOrn 4 . Taking into account that the synthetases involved in the bio- synthesis of the DKP-inheriting toxins thaxtomin and fumitremorgin also contain ... characterization of these compounds is growing and may result in the synthesis of specific inhibitors based on the structure of the pathogen siderophore [16]. A promi...

Ngày tải lên: 16/02/2014, 09:20

... interaction with the PDZ proteins: Mint-3, AMPA binding protein and gluta- mate receptor interacting protein (GRIP). It would therefore be interesting to determine whether this motif is also involved in ... identified the GRASP55 bind- ing site in the ICD of MT1-MMP, as well as the GRASP55 domains involved in the interaction with MT1-MMP ICD. We also describe the GRAS...

Ngày tải lên: 18/02/2014, 04:20

... C-terminal cysteine of the CXXC motif is proline (Fig. S6). In WhiB2 the absence of proline and therefore of the kink might not allow the protein to attain an optimal geometry, even though there is a CXXC ... mechanisms for resistance to intracellular killing, the scavenging of free radicals and the reactivation of degenerated proteins during infection by a family...

Ngày tải lên: 18/02/2014, 12:20

... mutant forms of MCPIP, either entirely lacking the PIN domain or with point mutations in this domain, were used. The results of experiments with actinomycin D indicate that lower levels of IL-1b ... on the type of MCPIP expressed by the vector introduced into these cells. In control cells (empty vector) and cells overexpressing a mutant form of MCPIP (without the P...

Ngày tải lên: 18/02/2014, 14:20

... 5333–5346 ª 2006 The Authors Journal compilation ª 2006 FEBS Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines Yuanying Ding 1 , Yong ... and protein are expressed in the eight human cancer cell lines examined, and HO-1 expression is detectable in five of the cell li...

Ngày tải lên: 19/02/2014, 05:20

... all the genes involved in the pathway in the same operon; the cell can then respond quickly to changes in the environ- ment by changing the expression of only a few genes and using the protein-synthesizing ... show that the data fit well with the indi- vidual determination of flux control coefficients by PFK, PK and LDH. The role of the las operon is dis...

Ngày tải lên: 19/02/2014, 17:20