Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: role of environmental factors pdf

... MINIREVIEW Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients Takuji Iwamoto 1,2 , Hiroshi Okamoto 1 , Yoshiaki Toyama 2 and Shigeki Momohara 1 1 Institute of Rheumatology, ... Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan Introduction Rheumatoid arthritis (RA) is a chronic systemic inflam- matory disease t...

Ngày tải lên: 18/02/2014, 18:20

... MINIREVIEW Molecular aspects of rheumatoid arthritis: role of environmental factors Shu Kobayashi, Shigeki Momohara, Naoyuki Kamatani and Hiroshi Okamoto Institute of Rheumatology, Tokyo ... genetic factors are responsible for 50–60% of the risk of devel- oping RA. Thus, environmental factors may explain the remaining risk of developing RA. A large variety of...

Ngày tải lên: 18/02/2014, 18:20

... MINIREVIEW Molecular aspects of rheumatoid arthritis: role of transcription factors Hiroshi Okamoto 1 , Thomas P. Cujec 2 , Hisashi Yamanaka 1 and Naoyuki Kamatani 1 1 Institute of Rheumatology, ... factors. In this review, we focus on the role of transcriptional factors on the pathology of rheumatoid arthritis (RA). Nuclear factor-jB The nuclear factor-jB (NF-jB)...

Ngày tải lên: 18/02/2014, 18:20

... molecular mode of action of glypho- sate and the molecular basis for glyphosate resistance. Structure and function of EPSPS EPSPS catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate ... GriP. Of partic- ular note is a short, 2.46-A ˚ hydrogen bond between N- e of His138 and a phosphate oxygen of GriP. Alanine substitutions at selected positions allowed...

Ngày tải lên: 14/02/2014, 14:20

... essen- tial role of the HR-A ⁄ B is to maintain the structural integrity of the HSF trimer, because an HSF deriva- tive containing the dimerization domain of transcription factor Gcn4 instead of the ... Sistonen L (2010) Regulation of the members of the mammalian heat shock factor family. FEBS J 277, 4126–4139. 3 Abane R & Mezger V (2010) Roles of heat shock factors in g...

Ngày tải lên: 18/02/2014, 04:20

... Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, University of Tokyo, Japan 2 Institute of Genetic Resources, Graduate School of Bioresource ... of the enzyme-excluded solution from that of the enzyme-containing solution and was expressed as nmols of 2,6-dichloroindophenol reduced per mg of protein per min. The extinc...

Ngày tải lên: 18/02/2014, 04:20

... (A) Scheme of the three-hybrid strategy used in the screen. (B) Number of colonies identified in each step of the screen. (C) Distribution of the 63 distinct sequences in relation of their position ... 3¢ UTR. In recent years, and as a result of great efforts aiming to understand the mechanism of RNA control in animals, the function of a diverse number of RNA-binding proteins...

Ngày tải lên: 18/02/2014, 06:20

... Approximately 0.4 mg of protein was treated with 10 mU of glycosidase F (Sigma-Aldrich Inc.) at 37 °C for 16 h. For crosslinking of proteins, slices of cotyledons were homogenized with 20 strokes of a Dounce ... S1. Comparison of intron–exon structures of GmPDIL-3a, GmPDIL-3b and orthologs of other plants. Fig. S2. Multiple amino acid sequence alignment of GmPDIL-3a, GmPDIL-...

Ngày tải lên: 18/02/2014, 11:20

... Ollivaux C & Soyez D (2000) Dynamics of biosynthe- sis and release of crustacean hyperglycemic hormone isoforms in the X-organ-sinus gland complex of the crayfish Orconectes limosus. Eur J ... Soyez D (2002) Enkephalinergic control of the secretory activity of neu- rons producing stereoisomers of crustacean hyperglyce- mic hormone in the eyestalk of the crayfish Orconectes lim...

Ngày tải lên: 18/02/2014, 11:20

... (2005) On the importance of carbohydrate- aromatic interactions for the molecular recognition of oligosaccharides by proteins: NMR studies of the struc- ture and binding affinity of AcAMP2-like peptides ... Use of the Amber force-field in conformational-analysis of carbo- hydrate molecules – determination of the solution conformation of methyl alpha-lactoside by NMR-spec- tros...

Ngày tải lên: 18/02/2014, 17:20