Tài liệu Báo cáo khoa học: The sequentiallity of nucleosomes in the 30 nm chromatin ﬁbre pptx

Tài liệu Báo cáo khoa học: Single phosphorylation of Tyr304 in the cytoplasmic tail of ephrin B2 confers high-afﬁnity and bifunctional binding to both the SH2 domain of Grb4 and the PDZ domain of the PDZ-RGS3 protein ppt

... 1. The eﬀect of tyrosine phosphorylations on the binding aﬃnity of ephrinB2 (301 –333) to the SH2 domain of Grb4 and to the PDZdomain of PDZ-RGS3. In the combination experiments, the two Cterminal ... PDZ binding on the interactions of the Grb4-SH2domain with the ephrinB2 (301 –333)-pY304 peptide. (A) The PDZ-binding curves are for the ﬂuorescein-labeled peptides including eph-rinB2 (301 –333) ... for the other ﬁve peptidesincluding ephrinB2 (301 –333), ephrinB2 (301 –333)-pY311,ephrinB2 (301 –333)-pY316, ephrinB2 (301 –333)-pY 330 andephrinB2 (301 –333)-pY331. None of these peptides can linkthe...

Tài liệu Báo cáo khoa học: Domain deletions and substitutions in the modular protein evolution doc

... domain deletions are more com-mon at either of the protein termini, and that theiroccurrence is slightly higher at one of the termini,depending on the number of domains in the proteinand the ... C−terminusLength of the N terminus in % of the deleted domainLength of the C terminus in % of the deleted domainPfam, N−terminus Pfam, C −terminusNumber of occurencesNumber of occurences2500035000550000 ... missing anywhere in the arrangement. Then we calculated the frequency of the deletion at each domain position within the group of proteins containing a given number of domains.We found that the...

Tài liệu Báo cáo khoa học: Tryptophan tryptophylquinone cofactor biogenesis in the aromatic amine dehydrogenase of Alcaligenes faecalis Cofactor assembly and catalytic properties of recombinant enzyme expressed in Paracoccus denitriﬁcans pptx

... substrate carbinolamine intermediate;III, iminoquinone intermediate; IV, product Schiff base intermediate;V, aminoquinol intermediate. In the oxidative half-reaction the ami-noquinol intermediate ... benzylamine (Fig. 5A) in comparison to the inhibition observed with tryptamine(Fig. 5B) suggests differences in binding of the twosubstrates within the active site of the enzyme and ⁄ orindicates ... kinetically in uentialionizations were identiﬁed in plots of klim⁄ Kd of pKavalues 7.1 and 9.3,again with the maximum value realized in the alkaline region. The poten-tial origin of these kinetically...

Tài liệu Báo cáo khoa học: Critical roles of Asp40 at the haem proximal side of haem-regulated phosphodiesterase from Escherichia coli in redox potential, auto-oxidation and catalytic control doc

... potential of the haem, rate constants o f CO, O2and CN b inding tohaem, and CD spectra in the Soret region [15–18],suggesting that this residue is critical for maintaining the electronic states of ... ncubated for 10 minprior to spectroscopic measurements.Cyanide binding The association rate of cyanide to haem was observed bymonitoring changes at 417 nm in spectra of the haemprotein in 50 mMTris/HCl ... binding accesschannel a t t he haem distal side and/or structure in t erms of cyanide binding in the Fe(III) complex.Redox potentials The redox state of haem is related to the PDE activity of Ec...

Tài liệu Báo cáo khoa học: Gene transcription of fgl2 in endothelial cells is controlled by Ets-1 and Oct-1 and requires the presence of both Sp1 and Sp3 pdf

... fetus and in regulatingimmune responses within the intestine. Induction of fgl2 in macrophages in response to viruses results in the production of a potent coagulant activity with the charac-teristics ... shown in Table 2 andFig. 5. Arrows indicate the bands that are interacting with theseprobes. All the lanes have labelled probes. The adding of extracts andcold probe are indicated in the top of ... constitutive or induced, remain unclear. Acomprehensive understanding of the general transcriptionmachinery on the native fgl2 promoter is necessary fordeveloping further insight into the TF-independent...

Tài liệu Báo cáo khoa học: NMR structure of AII in solution compared with the X-ray structure of AII bound to the mAb Fab131 pptx

... pointing in opposite directions. The stabilization of the folded conformation can be explained by the stacking of the Val3 side chain with the Pro7 ring and by a hydrophobiccluster formed by the ... possibly the result of twisting or bending in the middle of the amino-acidsequence of the hormone [49].Structure calculations and analysis The presence of conformational averaging in linear peptidescan ... between the termini and a hydrogen bond between the –NH3+terminal of Asp1 and the main chain carbonylgroup of Ile5 [30] . The second turn involves the residues Ile5,His6, Pro7, and the centre of...

Tài liệu Báo cáo khoa học: Human intrinsic factor expressed in the plant Arabidopsis thaliana doc

... malfunction of this Cblbinder hampers the uptake of the minute amounts of the vitamin present in food. Only around 1% of the ingestedCbl can be absorbed by passive diffusion [6].Classical vitamin B12deﬁciency ... sequence of matureIF. Approximately one-third of the protein was cleaved at the internal site …PSNPﬂGPGP. The key properties of the preparation obtained were identical to those of native IF: the binding ... Thus, the theoreticallycalculated extinction coefﬁcient of IF–CblOH2 in the UV-partofthespectrumwase280¼ 59 400ÆM)1Æcm)1according to eIF280¼ 40 300 ÆM)1Æcm)1 of the protein moi-ety...

Tài liệu Báo cáo khoa học: "THERE STILL IS GOLD IN THE DATABASE MINE" potx

... and mine it very deeply, not necessarily discovering every aspect of the domain but requiring that the various aspects be integrated with one another to produce a coherent whole. Even in the ... of our art? Instead of assuming that the problem is one of using typed English to access and/or update a file or files in a single database system, let us define a spectrum of potential natural ... ambiguity (the word "yield" is ambiguous if there is both financial and productivity data in the knowledge base), and other complex linguistic phenomena. Let us go on to define the other...

Tài liệu Báo cáo khoa học: Structural features of proinsulin C-peptide oligomeric and amyloid states pptx

... structural role in the proper foldingand disulﬁde bonding in insulin [2]. After proinsulincleavage, it is released to the blood together with insu-lin in equimolar amounts. The 31-residue peptide ... C-peptide in SDS solution represent the remaining population of NMR-visible monomersbecause the increasing fraction of oligomers (withincreasing SDS concentration) does not result in visibleNMR ... distribu-tion of 100 lM proinsulin C-peptide in the presence of divalent Ca2+and Mg2+ionsunder native conditions (B), and of 100 lMC-peptide in the presence of insulin (C) and of 100 lM...

Tài liệu Báo cáo khoa học: Novel aspects of heat shock factors: DNA recognition, chromatin modulation and gene expression ppt

... modules: the DNA-binding domain (DBD)at the amino-terminus and the oligomerization domain in the central region of the protein [1,4]. The HSFDBD belongs to the ‘winged’ helix-turn-helix family of DNA-binding ... Unlike other winged helix-turn-helix proteins, the wing of the HSF does not appear to contact the DNA. The wing of the Saccharomyces HSF is necessary forefﬁcient binding of a single trimer to the ... DBD–DBD interaction is important in the HSF–HSF and HSF–HSE interactions. In HSF DBD–HSE co-crystals, the protein–protein interface consists of the helix 2 amino-terminus, the turn and the wing[15]....

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Từ khóa: Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018 Báo cáo quy trình mua hàng CT CP Công Nghệ NPV Nghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoại Nghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấp Một số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTP Nghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THz Nghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt nam Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDE Phối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọ Nghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúng Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tin Thiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khí Chuong 2 nhận dạng rui ro Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vật chuong 1 tong quan quan tri rui ro Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật TÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ