Tài liệu Báo cáo " The extreme value of local dimension of c

Tài liệu Báo cáo khoa học: Erythrochelin – a hydroxamate-type siderophore predicted from the genome of Saccharopolyspora erythraea docx

... characterization of these compounds is growing and may result in the synthesis of speciﬁc inhibitors based on the structure of the pathogen siderophore [16]. A promising approach for the isolation of secondary metabolites, ... derivatization-based elucidation of the overall stereochemistry. Further- more, the functional properties of erythrochelin acting as an iron-che...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: X-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate docx

... [8,9]. One of the interesting features of the plant PSs is the presence of a conserved 24 residue insertion in the sequence [9]. This sequence of amino acids, which is missing in the sequence of bacterial ... pantothenate from low amounts of pantoate [9]. Here, we report the results of the structural studies of the pantoate-bound form of the N-terminal...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: Top-down MS, a powerful complement to the high capabilities of proteolysis proteomics pdf

... for covalent modiﬁcations of the enzyme, the effect of the inhibitor on the molecular mass value of HAD was measured; instead of an adduct increase, or no change, the value had unexpectedly decreased ... substitution; MS ⁄ MS will then show the substituent positions of dif- ferent isomers. A problem for MS ⁄ MS of either the peptides for the bottom-up approach...

Ngày tải lên : 18/02/2014, 16:20

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Tài liệu Báo cáo khoa học: Oxidized elaﬁn and trappin poorly inhibit the elastolytic activity of neutrophil elastase and proteinase 3 pdf

... binding of the methionine sulfoxide residue at the S 1 ¢ subsite of the active centers of NE and Pr3. The fact that the S 1 ¢ subsite of Pr3 is signiﬁcantly smaller than that of NE [21] might then explain ... dissociation of the oxidized inhibitor–NE complex was slow enough to be insigniﬁcant during the 20–60 s time period used to measure the activities of the...

Ngày tải lên : 19/02/2014, 07:20

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Tài liệu Báo cáo khoa học: Diversity and junction residues as hotspots of binding energy in an antibody neutralizing the dengue virus doc

... strongly decreased the rate of association, possibly by perturbing the topology of the electrostatic ﬁeld of the antibody. These data will help to improve the properties of mAb4E11 for therapeutic applications ... located at the center of the antibody combining site [18,19] and provide the major part of the free energy of interaction with the antigen [20,21]....

Ngày tải lên : 19/02/2014, 07:20

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Tài liệu Báo cáo khóa học: Trichostatin A reduces hormone-induced transcription of the MMTV promoter and has pleiotropic effects on its chromatin structure pptx

... and the cleavage of DNA by alkali [31]. The method allows easy detection of DNA–protein interactions via the N7 position of guanines in the major groove and via the N3 position of adenines in the ... coupled with the topology changes resulting from the loss of 1.5 superhelical turns of the DNA over the whole construct, suggest that the chromatin is indeed mor...

Ngày tải lên : 19/02/2014, 12:20

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Tài liệu Báo cáo khoa học: An immunomodulator used to protect young in the pouch of the Tammar wallaby, Macropus eugenii pptx

... (i.e. when the young has no immune system of its own), when there is a profound fall in the microbial ﬂora of the pouch [6]. Neither eugenin nor other low molecular mass components of the pouch ... as stimulation of the proliferation of lymphocytes, activa- tion of CCK receptors stimulate production of inter- leukins and secretion of immunoglobulins on the mucosal...

Ngày tải lên : 19/02/2014, 16:20

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Tài liệu Báo cáo khoa học: Control analysis as a tool to understand the formation of the las operon in Lactococcus lactis doc

... changing the expression of the respective genes. We found that neither the individual enzymes nor the sum of the las enzymes had signiﬁcant control on the glycolytic ﬂux at wild-type levels. The ... minute. The relative values of simultaneous modulation of the three las enzymes are calculated as the average of the three individual relative activities. Constru...

Ngày tải lên : 19/02/2014, 17:20

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Tài liệu Báo cáo khoa học: Long-distance interactions between enhancers and promoters The case of the Abd-B domain of the Drosophila bithorax complex pdf

... later than in the case of the histone gene cluster [10]. This difference in the tim- ing of somatic pairing perhaps reﬂects the difference between the complexities of the regulation of the two systems: ... placed outside the region deﬁned by the promoters of the two reporter genes (3¢ to one of them, Fig. 4, bottom), the PTS is able to overcome the enhancer...

Ngày tải lên : 20/02/2014, 01:20

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Tài liệu Báo cáo khoa học: "Using adaptor grammars to identify synergies in the unsupervised acquisition of linguistic structure" docx

... subtree in the parses of the other strings in the training corpus. A final accept-reject step cor- rects for the difference in the probability of the sam- pled tree under the adaptor grammar and the ... subset M of the nonter- minals are adapted. An adaptor grammar generates the same set of trees as the CFG with the same rules, but instead of defining a fixed pr...

Ngày tải lên : 20/02/2014, 09:20

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Tài liệu Báo cáo " The extreme value of local dimension of convolution of the cantor measure" docx

Tài liệu Báo cáo khoa học: Erythrochelin – a hydroxamate-type siderophore predicted from the genome of Saccharopolyspora erythraea docx

Tài liệu Báo cáo khoa học: X-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate docx