was recently identified in human peripheral blood monocytes treated with monocyte chemotactic protein 1 mcp1 and in human monocytederived macrophages stimulated with interleukin il1b these experiments revealed that the gene undergoes rapid and potent
báo cáo hóa học:" Survivin gene levels in the peripheral blood of patients with gastric cancer independently predict survival" doc
... 0.004Survivin* 1. 34 1. 14 1. 53 < 0.0 01 HR: hazard ratio; CI: confidence interval; * the HR associated with Survivin levels indicates the increase of death risk for 10 0-fold increase in Survivin expression. ... Medicine 2009, 7 :11 1 doi :10 .11 86 /14 79-5876-7 -11 1Received: 24 August 2009Accepted: 22 December 2009This article is available from: http://www.translational-medicine.com/content/7 /1/ 111 © 2009 ... patients'OS. The hazard ratio (HR) associated with Survivin levelsindicates the increase in risk of death for 10 0 fold increase in Survivin expression (Table 3).Since only these four independent...
- 8
- 565
- 0
Tài liệu Báo cáo khoa học: Staphylococcal enterotoxin C1-induced pyrogenic cytokine production in human peripheral blood mononuclear cells is mediated by NADPH oxidase and nuclear factor-kappa B doc
... superna-tant fluids of SEC1 -stimulated PBMC in rabbits was in parallel with the levels of interleukin- 1b and interleukin- 6 in the supernatants. The releaseof interleukin- 1b and interleukin- 6, nuclear translocation ... rabbits intravenously injected (1 mLÆkg )1 ) with the supernatant fluids obtained from PBMC (1 · 10 7cellsÆmL )1 ) treated for 72 h with the vehicle, SEC1 or SEC1 plus polymyxin B (50 lgÆmL )1 ). ... production(pgÆmL )1 )Fever index (°C)IL-1b IL-6Vehicle 12 ± 3 16 0 ± 7 0 .18 ± 0.02 (5)àSEC1 214 1 ± 5* 32500 ± 510 * 1. 06 ± 0.03 (5)*PDTC 13 ± 5 10 0 ± 3 0. 21 ± 0.02 (5)SEC1 + PDTC 17 6 ± 62 5500 ± 210 ...
- 13
- 465
- 0
Ruta 6 selectively induces cell death in brain cancer cells but proliferation in normal peripheral blood lymphocytes: A novel treatment for human brain cancer doc
... Ruta 1 was evaporated to approximately 10 0 µl, and 2 ml of RPMI medium was added to this. The plate was further incubated to evaporate the remaining alcohol.Of this medium 1 ml containing Ruta 1 ... compared with the control (10 .4%), showing its mitogenic effect on normalcells. In addition, the MI in H2O2only -treated B-lymphoidcells was 7 .1% compared with 14 .4% in cells treated with Ruta ... in 0.5 ml of a propidiumiodide (PI) solution (50 µg/ml PI, 0 .1% Triton X -10 0, and 0 .1 sodium citrate in PBS). These cells were incubated in PIsolution at 4˚C in the dark for 24 h and then the...
- 8
- 670
- 0
Báo cáo khoa học: Effect of 5-lipoxygenase inhibitor MK591 on early molecular and signaling events induced by staphylococcal enterotoxin B in human peripheral blood mononuclear cells doc
... determined. Gene name Sequence ID SEB (2 h) SEB (16 h) MK5 91 (2 h) MK5 91 (16 h)CTAP-III BC028 217 )1. 73 ± 0. 01 )2. 21 ± 0.03 1. 18 ± 0.03 1. 42 ± 0 .10 CTSL NM-0 019 12 6 .13 ± 0.22 4.9 ± 0 .15 )1. 01 ± 0 .10 ... & Suffredini AF (19 91) Detection of interleukin 8 and tumor necrosisfactor in normal humans after intravenous endotoxin: the effect of antiinflammatory agents. J Exp Med 17 3, 10 21 10 24.24 Yan ... believed that the gene analysiswould further complement and validate the inhibitoryeffects observed for MK5 91 at a protein level [18 ].Some of the investigated genes are involved in func-tions...
- 11
- 470
- 0
Pulmonary tuberculosis associated with increased number and percentage of natural killer and B cells in the peripheral blood pot
... with the clinical findings. Peripheral blood subset data of the patients were compared with a section of the similar data generated previously for defining the normal range of adult peripheral ... lymphocytes in the peripheral blood. There was however no difference in the percentages of CD8 + and cells expressing HLA-DR molecules between the patients with PTB and normal healthy individuals. ... T-lymphocyte counts in adults infected with human immunodeficiency virus through blood and plasma sold in the past in china and in whom infection has progressed slowly over a long period. Clin. Diagn....
- 5
- 419
- 0
Báo cáo sinh học: "Concomitant detection of IFNa signature and activated monocyte/dendritic cell precursors in the peripheral blood of IFNa-treated subjects at early times after repeated local cytokine treatments" doc
... stimulusGO:00 313 47GO:0045087GO:004 312 3GO:0002253GO:0002252GO:0050778GO:0048584GO:0006954GO:0009 611 GO:0006952GO:0048 518 GO:0006950GO:00 517 04GO:0006955GO:0002376GO:00508969.6x10-38.5x10-32.4x10-32.2x10-3 1. 1x10-32.0x10-44.4x10-45.9x10-49.6x10-42.2x10-67.4x10-23.1x10-3 1. 3x10-93.3x10 -11 6.3x10-92.2x10-6ABFigure 4 Functional classification of genes ... locusUBE2L6BST2SF3B4G1P2IFIT2IFITM2SILVIRF7NTRK2TNFSF10CHERPNMISP 110 STAT1TRIM22C1orf29MYD88IFI35IFITM2LY6EIFITM3SERPING1ADARMX1MX2GMPRIFIT1LIPCMMP1CXCL10OAS1 10 328 11 73742 13 8 13 3674 13 10 14 15 9HBV StudyMelanoma StudyPBMC In vitro Monocytes In vitroPre IFND Post IFND252CD14+ IFNDCD14 ... typical IFNa-induced genes.CD14+/CD16+ monocytes, coexpressing CD16 and lowlevels of CD14, wer e first characterized by Ziegler-Heitbrock and colleagues in 19 88 [ 41] , and their number and phenotype/function...
- 15
- 526
- 0
Báo cáo khoa học: Plasmodium falciparum merozoite surface protein 1 Glycosylation and localization to low-density, detergent-resistant membranes in the parasitized erythrocyte pdf
... findings indicated that [3H]GlcN is linked toserines and [17 ,37,38] threonines [7 ,10 ] and we now show that O-GlcNAc addition takes place in both the C- and N-terminal ends of the protein, while the ... linked to the surface of the protein in a-O-GlcNAc configuration. Twoa-O-GlcNAc sites are indeed predicted in the Ghana,PngMAD20 and Uganda strain MSP -1 proteins and it isremarkable that the three ... Uganda vs. Thai-K1 and Wellcome). Suchb-O-GlcNAc sites are not localized in the regions ofhomology (387– 413 and 11 00 11 87) within the sequencesof blocks 5 16 of the two dimorphic forms. The...
- 10
- 415
- 0
Báo cáo khoa học: Cdc37 maintains cellular viability in Schizosaccharomyces pombe independently of interactions with heat-shock protein 90 doc
... domains, including the postulatedHsp90-binding and dimerization regions [16 ]. Mutants with truncations extending into the N-terminaldomain, Cdc37 (1 15 5), Cdc37 (1 12 0), Cdc37 (1 60) and Cdc37 (1 37), ... mine the identity and location of the nucleotide insertion.Four mutants obtained contained in- frame insertionsresulting in the insertion of five amino acids into the Cdc37 protein. Stop ... into the Nde1-Xma1 sites of pREP1 and pREP 81 vec-tors. Similarly, S. cerevisiae CDC37 was amplified from the plasmid E 119 [30] by PCR and ligated into the Nde1-Xma1sites of the vectors pREP1...
- 12
- 275
- 0
Báo cáo khoa học: Transcription factor specificity protein 1 (SP1) and activating protein 2a (AP-2a) regulate expression of human KCTD10 gene by binding to proximal region of promoter pot
... FEBS 11 19Binding of Sp1 and AP-2a to the correspondingsites in the promoter of human KCTD10 in vivoTo confirm that Sp1 and AP-2a bind to the authen-tic endogenous cis-elements in the KCTD10 ... accepted 11 December2008)doi :10 .11 11/ j .17 42-4658.2008.06855.xPotassium channel tetramerization domain-containing 10 gene (KCTD10)belongs to the polymerase delta-interacting protein 1 (PDIP1) gene ... genomic fragment in the 5¢-flanking region of human KCTD10; and identified the binding sites of two transcription factors, specific-ity protein 1 (SP1) and activating protein- 2a (AP-2a), in the promoter...
- 11
- 409
- 0
báo cáo hóa học:" Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells" pptx
... provide insight into gene reg-ulation within tissues, the induction of ABCA1 and ABCG1 within the spleen, an organ highly enriched in immune system cells, was compared to induction in peripheral blood ... lesions [13 -15 ]. In macrophage, LXR activation results in the induction of several genes. Among these induced genesare those encoding the ATP-binding cassette proteins,such as ABCA1 and ABCG1, which ... vivo with LXR-623, which showed that ABCA1 and ABCG1 expression was similarly regulated in human peripheral blood cells. Furthermore, despite the assumption that monocytes (the circulating macrophage-Journal...
- 15
- 623
- 0
báo cáo hóa học:" Cyclic changes in gene expression induced by Peg-interferon alfa-2b plus ribavirin in peripheral blood " pot
... 1 4 98 3.7E+05 15 51 61 1a 0 3 73 1. 8E+06 16 50 78 1a 1 3 99 1. 6E+06 17 60 10 6 1a 1 2 37 4.1E+05 18 45 11 4 1a 1 4 16 1 9.0E+05 19 47 74 1b 1 3 11 7 4.0E+0520 61 83 1b 1 2 18 1 8.1E+05 ... 2 12 7 1. 1E+078 42 11 2 1a 1 1 67 7.2E+06952 78 1a 1 4 71 2.3E+06 10 57 76 1b 0 2 68 7.1E+06 11 59 70 1b 0 3 62 2.4E+06 12 56 10 9 1a 1 4 74 5.8E+06 13 49 11 6 1a 1 2 44 5.8E+06 14 53 90 1b 1 4 ... of these genesmay represent compensatory responses.SP100 1. 9 1. 7 1. 9 1. 6 1. 6 1. 5 1. 8 SP100 nuclear antigenSP 110 1. 9 1. 5 1. 9 1. 5 1. 5 1. 5 1. 6 SP 110 nuclear body protein USP18 7.4 4.9 7.5 5.1...
- 15
- 646
- 0
báo cáo hóa học:" High correlation of the proteome patterns in bone marrow and peripheral blood blast cells in patients with acute myeloid leukemia" pot
... urine total protein. Ann Clin Bio-chem 19 87, 24(Pt 2) :14 0 -14 4.Table 3: Proteins as expressed in the gastric cell line but not in AML.No. Protein name General function Ref. 414 -3-3σ Adapter protein ... of the gel [14 ].After electrophoresis, the gels were fixed in 50% ethanol, and 10 % acetic acid for 12 hours.Silver stainingProteins were visualized using the silver staining methodemploying ... related) was only present in patient C, spot No. 12 1 and 12 2 (TCHTP and variant) was only present in patient F and G, respectively. Spot 60 (FK506 binding pro-tein 4) was absent in patient D and...
- 8
- 529
- 0
báo cáo hóa học:" yuDetecting the percent of peripheral blood mononuclear cells displaying p-STAT-3 in malignant glioma patients" pot
... weremoved the paraformaldehyde by pelleting the cells at 15 00 rpm for 5 min, resuspending them in prechilled90% methanol, and incubating them on ice for 30 min. The cells were then pelleted at 15 00 ... The cells were then centrifuged at 15 00 rpm for 2.5 min and washed once with FACS buffer and 3 times with 1: 3 PermWash (eBioscience). The cellswere stained intracellularly with 5 μL PE-antihumanFoxP3 ... [43], and Janus kinase 2 [46], and it is uncertainwhich of these, either individually or in combination, is the etiological agent for inducing p-STAT-3 in PBMC.Alternatively, there may be other...
- 9
- 462
- 0
Báo cáo hóa học: " Human cord blood progenitors with high aldehyde dehydrogenase activity improve vascular density in a model of acute myocardial infarction" ppt
... Stratifying the mice based on the day 0 infarct size in the presentstudy did not, however, influence the interpretation of the data and all transplanted animals were included in the final evaluation.NOD/SCID ... crystals(QD655, Invitrogen) in cell media (X-Vivo with recom-binant human SCF, Flt3-L and TPO (all 10 ng/ml)) in thepresenceof0.1nMprotaminesulphatefor15minfollowed by overnight incubation in cell ... [18 ] and transplanted with QD655 or Feridex750 labeledcells (2 × 10 6CD34+ ,1. 6-4 10 5ALDHloLin-;2.3-4 10 5ALDHhiLin-)byasingleintravenous(IV)injec-tion via the tail vein. PBS injected...
- 13
- 506
- 0
Báo cáo sinh học: "Interferon signaling patterns in peripheral blood lymphocytes may predict clinical outcome after high-dose interferon therapy in melanoma patients" potx
... RP,Larner AC, Finbloom DS: Interleukin -10 inhibits expression of bothinterferon alpha- and interferon gamma- induced genes by suppressingtyrosine phosphorylation of STAT1. Blood 19 99,93 :14 56 -14 63.32. ... fold induction of pSTAT1 in post -treated lymphocytes by the fold induction of pSTAT1 in pre -treated lymphocytes (post/pre). A median of these ratios was generated (1. 25) using all patients in the ... ned by dividing the fold change in pSTAT1 post-treatment by the foldchange in pSTAT1 pre-treatment. A median of these ratios was generated using all patients in the stu dy (n = 14 ) and patients...
- 9
- 369
- 0
- and in several species that have been closely examined
- metallothionein mt was first identified in 1957 by m margosch and b vallee as a cadmium protein from equine kidney cortex in fact
- with some six billion mobile subscriptions now in use worldwide
- in sickness and in health
- news blogs and in public
- ± pss 25 1 power and energy in circuits mastering physics
- pss 25 1 power and energy in circuits mastering physics
- tiếng anh lớp 10 unit 1 a day in the life of
- english for tourism and hospitality in higher education studies course book with audio cds
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25