... content ofthe instrument is reflective ofthe Mestizo multicultural-multiracial world view.7. The structure ofthe instrument is reflective ofthe Mestizo view.8. The demands ofthe instruments ... thought of as being part of a disease(Kleinman, 1988). The lack of understanding of this difference hampered the under-standing ofthe role of culture on health for many years. Culture has a profoundimpact ... aspect of this process, accord-ing to Erikson, is the development of a sense of continuity between the way otherssee the individual andthe way the individual sees him- or herself. The result of...
... incentives the hard glare of a passer-by and the offender’s feelings of guilt—are at least as powerful as finan-cial and legal incentives. If social forces get us most ofthe way there, how ... that the outcome of that election came down to a handful of voters; but their names were Kennedy, O’Connor, Rehnquist, Scalia and Thomas. And it was only the votes they cast while wearing their ... out the effect ofthe money. As with the police/crime rate puzzle, he had to trick the data. Because he himself had typed in the data, he had noticed some-thing: often, the same two candidates...
... and conditions of license. Color Atla s of Pharmac ology3rd edition, revisedand expanded Heinz Lüllmann,M.D.Former Professor and ChairmanDepartment of PharmacologyUniversity of KielGermanyKlaus ... analgesic ibuprofen. The excess of analogue preparations and the unnecessary diversity of trade names foroneandthesamedrugmakethepharma-ceutical markets of some countries (e. g.,Germany) rather perplexing. ... knowledge ofthe preventive and therapeutic value of drugs is a sine quanon for the successful treatment of patientsentrusting themselves to a physician orpharmacist.Because ofthe plethora of proprietary...
... DPP-IV). Another potential bond can beproposed between the OH atom of Tyr380 andthe car-bonyl group ofthe ligand. Finally, the valine sidechain ofthe ligand, pointing towards the active ... be the reference); 2, docked into the active site of the human DPP-IV; 3, docked into the active site ofthe crystalline structure of PepX from L. lactis ;and4 , docked into the active site ofthe ... 2). The interactions ofthe bound ligand with the resi-dues ofthe specificity site (Fig. 4A) reveal good stack-ing between the pyrrolidine ring ofthe drug and the side chain of Tyr380 (Pos1 subsite),...
... the changes introduced in the redox cofactor environment upon complex formation. Theyare therefore related to the specificity andthe strength of the protein–protein interaction. Therefore, the ... determination of a Kdvalue of 25 ± 3 lMfor the [FNRox:Adxox] complex andof 17 ± 2 lMfor the [FNRox:Adx(4–108)ox] complex (Table 1).Study ofthe kinetics of reduction of WT Adx by ... physiologicalsignificance and support the hypothesis ofthe existence of aternary ET [Adx:Adx:AdR] complex in the physiologicalAdR/P450 system [16,36,37]. Therefore, our experimentaldata for the reduction of Adx...
... to a person (The Wizard) at another terminal who answered the subject's requests by consulting paper copies ofthe database tables. The experimenter then gave the details ofthe two tasks. ... consult the 3.1.1 Operators andthe explicit specification of set properties The task of database access involves the construction and manipulation of answer sets with various prop- erties. The ... order. These would involve two operations, the first would be the generation of a set, andthe sec- ond the sorting of that set in terms of some attribute such as age or date. The unknown...
... costs of normal pressure rectification. Dependingon the difference between the temperatures at the bottom tW and at the top tD of the column, and on the price ofthe heating steam CH, the optimum ... experimental data on the hydraulicbehaviour of packed columns for the development of a new method for the standardpresentation ofthe fluid dynamics of columns with any type of packing design. The basicprinciples ... pressuredrop above the loading line as well as separation efficiency at the minimum ofthe curvent/H = f(uV). The advantages ofthe method developed by Beck lie mainly in the sim-ple use ofthe correlations,...
... food stocks, andthe mood ofthe garrison. The tactics of the Daily Mail captured the attention ofthe nation; the newspaperdramatized the situation ofthe town by emphasizing the danger that ... notions of Boer inhumanity towardAfricans, the pro-war argument ofthe ‘‘negrophilists.’’ The other cat-egory into which mentions of Africans fall is praise ofthe loyalty of the Cape Boys andthe ... hierarchies of race, sex, and class and ofthe ways in which, hand in hand, the New Imperialism and the New Journalism brought Britain into the twentieth century. The war at home which included the...
... (such as the booby-trapping of temples), the use of poison, the destroying of wells andthe sowing of dissension in the enemy’s ranks.46Thestruggleformoderationinwarhasbeenalongone – and one ... world of inde-pendent political communities bound together by the rule of law ratherthan by the sovereignty of a single emperor. The Chinese can thereforebe said to have been the pioneers ofthe ... the law of war. It tells the story, in narrative form, of the interplay through the centuriesbetween,ontheonehand,legalideasaboutwarand,ontheotherhand,statepracticeinwarfare.Neffcovers the emergence,...
... (92.34(78.8)69.8)796avgqpsf++∆==Therefore, the average pressure increase in the clay layer is, The pressure poat the center ofthe clay layer is,po= γsandh sand+ γ’sandh’sand+ γ’clayh’clay= (100)(4) ... being designed for a small office building with a total live load of 250 kips and dead load of 500 kips. Find: (a) the depth Dffor a fully compensated foundation, (b) the depth Dfif a soft ... in the x and y values, which these values are found by using the x-y coordinate system off the mat foundation. Determine the average soil reaction. (92.34(78.8)69.8)796avgqpsf++∆==Therefore,...
... men and 0.1–0.6% inwomen [2]. The prevalence rises to 4.4% of men and 1.8% of women over the age of 65 [4]. A two-fold increase inincidence of gout has been reported in the USA and NewZealand ... publication was obtained from the patient. The authors wish to thank Dr. William Hsu and Dr. Tania Pringle for their contribution to the interpretation ofthe radiographs and providing key information ... thatthese were most likely due to old trauma. Mild osteoar-thritic changes were noted at the carpal-metacarpal jointat the base ofthe thumb. The report stated that the radio-graphs were otherwise...
... role in the pathogenesis of both types of diabetes mellitus. High levels offree radicals andthe decline of antioxidant defense mechanisms lead to damage of cellular or-ganelles and enzymes, ... (maximum of 3 milliAm-peres) of one polarity for 11.5 minutes, which then switched to the opposite polarity for another 11.5 minutes. The device was designed to switch the di-rection of current ... Popliteal and pedal pulses were absent bilaterally with poor capillary re-fill. The left foot was red and inflamed up to and in-cluding the medial malleolus. The lateral aspect ofthe great toe and...