5  complications associated with bisphosphonate therapy

... associated with dasatinib therapy Fluid retention AEs have been associated with all three BCR-ABL inhibitors currently on the market, but pleural effusions may be more common with dasatinib therapy ... of edema Pleural effusions is uncommonly associated with nilotinib therapy (1%) [30] Management of these AEs is best treated with dose interruptions, and therapy can be resumed at the 400 mg once ... Toxicities of Dasatinib The side effects associated with dasatinib therapy are predominantly mild or moderate (grade or by the National Cancer Institute Cancer Therapy Evaluation Program criteria),...

Ngày tải lên: 10/08/2014, 22:20

... complications associated with large-bore tubes Our study confirms the risk of inadvertent tracheopulmonary insertion of enteral feeding tubes and the significant morbidity and mortality which can be associated ... enteral feeding These smaller tubes decreased the risk of ulceration of the nose, pharynx and stomach associated with the larger-bored and more rigid type [11] However, it was not long after the narrow-bore ... complications began to be reported There have now been over 100 reported cases of tracheopulmonary injuries associated with insertion of these feeding tubes [12] In our study, narrow-bore enteral feeding...

Ngày tải lên: 12/08/2014, 18:20

... peptides after hormone replacement therapy in postmenopausal women Clin Sci (Lond) 2001; 101: 447-53 20 Kanda H, Kita Y, Okamura T, et al What factors are associated with high plasma B-type natriuretic ... medications 150 In the Japanese population, it has been reported that plasma BNP levels are positively associated with age, urinary salt excretion, higher blood pressure, a high R-wave voltage in the ... multivariate models adjusting for known risk factors, showed that elevated plasma BNP levels were associated with an increased risk of blood pressure progression in males but not in females However,...

Ngày tải lên: 26/10/2012, 10:04

... in plasma and vaginal secretion supernatant samples was collected by centrifugation and virion -associated HIV-1 RNA copies were quantified using the Roche Amplicor™ Ultra-Sensitive HIV-1 Monitor ... in vaginal secretions, while 32.6% shed X4-like genotypes To identify viral and clinical factors associated with vaginal X4- or R5-like genotypes, we evaluated plasma and vaginal viral levels, ... lymphoctye counts using Chi-square and Fisher's exact tests (Table 1) R5-like vaginal HIV genotypes were associated with high levels of plasma virus and the absence of ART Table 1: Vaginal Genotypic Associations...

Ngày tải lên: 20/06/2014, 01:20

... compared with 25 g/L was associated with a nearly 50% reduced hazard of mortality (AHR 0.52 [0.38, 0.70]) Conversely, higher baseline serum ferritin and hsCRP levels were associated with increased ... baseline serum level of 250 μg/L was associated with an approximate 67% increased hazard of mortality at 12 weeks (AHR 1.67 [1.30, 2.15]), and a value of 1000 μg/L was associated with a nearly 10-fold ... infections or inflammation -associated, non-AIDSdefining events In this observational cohort study, pre-treatment phosphate, albumin, ferritin and hsCRP serum levels were associated with mortality...

Ngày tải lên: 20/06/2014, 08:20

... stage 2) at enrolment was associated with lower CrCl, but not with lower eGFR Lower enrolment weight was associated with lower CrCl, but in contrast, lower weight was associated with higher eGFR ... lower haemoglobin at enrolment were all significantly associated with both a CrCl < 60 mL/min and eGFR < 60 mL/min/ 1.73 m2 Being female was associated with lower eGFR, but not with lower CrCl, ... significantly associated (HR, 1.34; 95% CI, 1.23-1.52; p < 0.0001) with shorter times to meeting cART initiation criteria Having an eGFR < 60 mL/min/1.73 m2 (Table 3, Model 1) was significantly associated...

Ngày tải lên: 20/06/2014, 08:20

... combined R203 Arthritis Research & Therapy Vol No Forsblad d’Elia et al Table Baseline data of postmenopausal women with rheumatoid arthritis in the hormone replacement therapy (HRT) group and the control ... IL-6, TNF-α, and IL-1Ra at baseline IL-6 in serum was highly associated with ESR (Fig 1a) and, to a smaller degree, was inversely associated with IGF-1 TNF-α was also significantly connected ... Research & Therapy Vol No Forsblad d’Elia et al a minor extent in sIL-6R and was inversely correlated with the change in IGF-1 The alteration in ESR was to a small degree inversely associated...

Ngày tải lên: 09/08/2014, 01:21

... immunoablative therapy ('pre-TX'), the lowest antibody level after immunoablative therapy ('nadir'), the period after immunoablative therapy without disease-modifying antirheumatic drug (DMARD) therapy ... reductions in ACPA-IgG levels were associated with clinically prolonged responses to immunoablative therapy The susceptibility of ACPA-IgG to immunoablative therapy was associated with a high degree ... http://arthritis-research.com/content/9/5/R106 Figure Effects of immunoablative therapy Shown are the effects of immunoablative therapy on rheumatoid arthritis (RA)-specific autoantibody responses, therapy physiological antibody responses...

Ngày tải lên: 09/08/2014, 10:21

... extracorporeal photochemotherapy [15,16] Indeed, the beneficial effects of extracorporeal photochemotherapy in the treatment of severe chronic or acute graft-versus-host disease have been associated with ... the TGFβ signaling pathway has also been shown to be critical for natural Treg development [10] associated with an increase in circulating levels of TGFβ accompanied by a decrease in inflammatory ... efficiency of apoptotic cell infusion to modulate the arthritic response The feasibility of cellular therapy based on the immunomodulatory properties of apoptotic cells has already been evaluated in...

Ngày tải lên: 09/08/2014, 14:22

... Arthritis Research & Therapy Vol 11 No Raterman et al Table Characteristics of the study population MetS presenta n = ... methotrexate; RA, rheumatoid arthritis; SSZ, sulfasalazine; TNF, tumour necrosis factor Table Variables associated with metabolic syndrome Multivariatea Univariate OR Body mass index 95% CI P value OR...

Ngày tải lên: 09/08/2014, 14:22

... Arthritis Research & Therapy Vol 11 No Toms et al Competing interests The authors declare that they have no competing ... Institute, Athens, Greece References Toms TE, Panoulas VF, Douglas KMJ, Kitas GD: Methotrexate therapy associates with a reduced prevalence of the metabolic syndrome in rheumatoid arthritis patients...

Ngày tải lên: 09/08/2014, 14:22

... more immuno-compromised when therapy was initiated suggesting that IRIS may be associated with persistent hyperactivation of both CD4 and CD8 T lymphocytes, and associated with a lack of naïve ... Hospital, London, UK were studied Four presented with MAC -associated IRIS, and where acid-fast bacilli were detected, patients were given anti-MAC therapy as soon as diagnosed These patients had a median ... undetectable in all patients at presentation of IRIS IRIS patients (n = 4) received immunotherapy as salvage therapy consisting of IL-2 (Chiron Therapeutics, Uxbridge, UK) at million units twice...

Ngày tải lên: 11/08/2014, 10:23

... Acute eosinophilic pneumonia associated with antidepressant agents Pharm World Sci 1999, 21:241-242 Haro M, Rubio M, Xifre B, Castro P: [Acute eosinophilic pneumonia associated to sertraline] Med ... lung shows a histological pattern of fibrotic NSIP with diffuse established interstitial fibrosis associated with moderate chronic inflammation (×20 magnification) 2b) The lung at high power, shows ... of the patient's usual psychiatric team haloperidol was introduced as replacement anti-psychotic therapy For the pulmonary fibrosis, treatment was commenced with intravenous methylprednisolone...

Ngày tải lên: 11/08/2014, 17:21

... retrospective analysis was conducted of all patients who received a diagnosis of hypercalcemia associated with oral cancer at the Department of Oral and Maxillofacial Surgery of University of ... patients were treated with BPs for CAH (BP group) The remaining patients did not undergo a specific therapy for CAH (non-BP group) On average, the BP group was significantly younger and showed significantly ... 0.427 0.871 0.186 *: Mann-Whitney test There was no significant difference in the survival time associated with any of the clinical and laboratory characteristics except the administration of...

Ngày tải lên: 11/08/2014, 23:22

... neurotransmission observed in AD [7] Processing of α-amyloid protein to βamyloid peptide is also associated with the AD-related neurofibrillary tangles [6] The relationship between AD and the formation ... differences allow the medicinal chemist to explore the region specific for BChE so that a combination therapy can be employed As a drug target, it has been observed that BChE inhibition may also be ... [15-24] Benzothiazepine derivatives, two seven-membered N and S heterocyclic ring systems, have been associated with broad spectrum biological activities [25] Continuing our ongoing research for new...

Ngày tải lên: 13/08/2014, 16:20

... second, the issue of appropriate dosing and duration of NAC treatment The concept of tailormaking NAC therapy to the APAP-poisoned patient has been raised recently in the literature [14,15], and differing ... clinicians may have to consider individual case scenarios in tailor-making duration and dose of NAC therapy Competing interests The authors declare that they have no competing interests References...

Ngày tải lên: 13/08/2014, 16:20

... was assumed that abdominal surgery is probably associated with an increased likelihood of developing AKI The appropriate timing of renal replacement therapy (RRT) initiation in patients with AKI ... postoperative acute renal replacement therapy Intensive Care Med 2008, 34:101-108 Lindenauer PK, Pekow P, Wang K, Mamidi DK, Gutierrez B, Benjamin EM: Perioperative beta-blocker therapy and mortality after ... YW, Chen YM, Hu FC, Lin YH, Tsai PR, Wu KD: Early renal replacement therapy in patients with postoperative acute liver failure associated with acute renal failure: effect on postoperative outcomes...

Ngày tải lên: 13/08/2014, 19:20

... was associated with treatment success (10, 20) However, other studies demonstrated that weight loss did not improve the treatment outcomes (15, 21) It is known that interferon therapy is associated ... (thrombocytopenia) at the end of treatment was associated with SVR (P=0.05) Age, ethnicity, 38 gender, drug abuse, and histology were not significantly associated with SVR To allow for clinical applicability, ... treatment associated independently with HCV genotype1 infection but a better response with weight loss (18) Limited knowledge exists regarding the influence of on-treatment factors during therapy...

Ngày tải lên: 26/10/2012, 09:39

... to eradicate minimum residual CML cells which survived long-term imatinib therapy, we started WT1 peptide vaccination therapy in combination with imatinib in a CML patient who could not acquire ... anti-tumor immunotherapy as in this case These data suggested the possible usefulness of treatment for suppressing the function of regulatory T cells in combination with anti-tumor immunotherapy including ... several laboratories [4-6] WT1 peptides have already been used in clinical trials for specific immunotherapy of HLA-A24+ patients with brain tumor, breast cancer, colorectal cancer, thyroid cancer,...

Ngày tải lên: 26/10/2012, 09:39

... study’s main finding is that the changes in serum total cholesterol concentrations are clearly associated with those of aspirin esterase activity during a period of physical activity modification ... metabolism among older people A recent report has shown that greater aspirin hydrolysis can be associated with decreased cholesterol levels of high-density lipoprotein in type diabetics (6) Although ... coronary artery bypass grafting is transient: impact on the monitoring of aspirin antiplatelet therapy Ther Drug Monit 2005; 27: 484-90 Gresner P, Dolník M, Waczulíková I, et al Increased blood...

Ngày tải lên: 26/10/2012, 09:39