xxixContents 49 Acute Viral Bronchiolitis 546 Katherine N Slain and Steven L Shein 50 Asthma 552 Steven L Shein, Richard H Speicher, Howard Eigen, and Alexandre T Rotta 51 Neonatal Pulmonary Disease 5[.]
Contents 49 Acute Viral Bronchiolitis 546 Katherine N Slain and Steven L Shein 50 Asthma 552 Steven L Shein, Richard H Speicher, Howard Eigen, and Alexandre T Rotta 51 Neonatal Pulmonary Disease 568 Thomas M Raffay and Richard J Martin xxix 64 Status Epilepticus 779 Edward E Conway Jr and Robert C Tasker 65 Hypoxic-Ischemic Encephalopathy 793 Ericka L Fink, Mioara Manole, Robert S.B Clark, Cameron Dezfulian, and Patrick M Kochanek 66 Pediatric Stroke and Intracerebral Hemorrhage 811 Catherine Amlie-Lefond and Jeffrey Ojemann 52 Pneumonitis and Interstitial Disease 585 Daiva Parakininkas 53 Diseases of the Pulmonary Circulation 608 Hui Zhang, Christine Vohwinkel, Aline Maddux, and Kurt R Stenmark 54 Mechanical Ventilation and Respiratory Care 625 Kyle J Rehder and Ira M Cheifetz 55 Noninvasive Ventilation in the Pediatric Intensive Care Unit 644 67 Central Nervous System Infections and Related Conditions 823 Kevin M Havlin, Charles R Woods Jr, and Mark E Rowin 68 Acute Neuromuscular Disease and Disorders 837 Maria Weimer, James J Reese Jr, and Ann H Tilton 69 Acute Rehabilitation and Early Mobility in the Pediatric Intensive Care Unit 845 Hallie Lenker, Yun Kim, Beth Wieczorek, and Sapna R Kudchadkar Omar Alibrahim and Katherine N Slain 56 Extracorporeal Life Support 655 Heidi J Dalton, Nina Censoplano, Tom Preston, Hanneke Ijsselstijn, and Aparna Hoskote 57 Pediatric Lung Transplantation 679 Carol Conrad Section VII: Pediatric Critical Care: Renal 855 70 Renal Structure and Function 856 Matthew M Grinsell and Victoria F Norwood 71 Fluid and Electrolyte Issues in Pediatric Critical Illness 866 Idris V.R Evans and Emily L Joyce Section VI: Pediatric Critical Care: Neurologic 689 72 Acid-Base Disorders 882 58 Structure, Function, and Development of the Nervous System 690 73 Tests of Kidney Function in Children 896 Robert S.B Clark and Michael Shoykhet 59 Critical Care Considerations for Common Neurosurgical Conditions 710 Peter F Morgenstern, Robert H Bonow, Isaac Josh Abecassis, Samuel R Browd, and Amy Lee 60 Neurologic Assessment and Monitoring 720 Mark S Wainwright and Sue J Hong 61 Neuroimaging 735 Francisco A Perez, Hedieh Khalatbari, and Dennis W.W Shaw 62 Coma and Depressed Sensorium 756 Neethi Pinto and Casey Stulce 63 Intracranial Hypertension and Monitoring 768 Robert C Tasker and Alireza Akhondi-Asl Michelle C Starr and Shina Menon Rajit K Basu 74 Glomerulotubular Dysfunction and Acute Kidney Injury 907 Timothy E Bunchman, Vu Nguyen, and Michelle L Olson 75 Pediatric Renal Replacement Therapy in the Intensive Care Unit 923 Raj Munshi and Jordan M Symons 76 Pediatric Renal Transplantation 930 Jodi M Smith, André A.S Dick, and Ruth McDonald 77 Renal Pharmacology 937 Jenna R Nickless, Victoria Chadwick, and Heidi Yu 78 Acute Severe Hypertension 945 Joseph T Flynn xxx Contents Section VIII: Pediatric Critical Care: Metabolic and Endocrine 959 Section X: Pediatric Critical Care: Gastroenterology and Nutrition 1129 79 Cellular Respiration 960 94 Gastrointestinal Structure and Function 1130 Scott L Weiss, Clifford S Deutschman, and Lance B Becker 80 Biology of the Stress Response 971 Stephen Wade Standage Lee M Bass and David M Steinhorn 95 Disorders and Diseases of the Gastrointestinal System 1141 Lauren Bodilly and Samuel A Kocoshis 81 Inborn Errors of Metabolism 976 Cary O Harding and Amy Yang 96 Acute Liver Failure 1155 Hengqi (Betty) Zheng, Mihaela A Damian, and Simon Horslen 82 Progress Towards Precision Medicine in Critical Illness 991 Mary K Dahmer and Michael W Quasney 83 Molecular Foundations of Cellular Injury 996 Jocelyn R Grunwell and Craig M Coopersmith 97 Hepatic Transplantation 1162 Patrick J Healey, Britt Julia Sandler, Abigail Apple, Thomas V Brogan, and Jorge D Reyes 98 Acute Abdomen 1170 Robert Sawin, Rebecca Stark, and Derya Caglar 84 Endocrine Emergencies 1003 Katherine Ratzan Peeler and Michael S.D Agus 99 Nutrition of the Critically Ill Child 1177 Ben D Albert and Nilesh M Mehta 85 Diabetic Ketoacidosis 1016 Ildiko H Koves and Nicole Glaser Section XI: Pediatric Critical Care: Immunity and Infection 1189 Section IX: Pediatric Critical Care: Hematology and Oncology 1023 100 Innate Immunity 1190 86 Structure and Function of the Hematopoietic Organs 1024 101 Adaptive Immunity 1199 Seth J Corey and Julie Blatt 87 The Erythron 1033 Allan Doctor, Ahmed Said, and Stephen Rogers 88 Hemoglobinopathies 1040 M.A Bender and Anne Marsh Samiran Ray, Rachel S Agbeko, and Mark J Peters Jennifer A Muszynski, W Joshua Frazier, and Kristin C Greathouse 102 Critical Illness and the Microbiome 1208 Rafael G Ramos-Jimenez, Dennis Simon, and Michael J Morowitz 103 Congenital Immunodeficiency 1215 Hannah Laure Elfassy, Troy Torgerson, and Christine McCusker 89 Coagulation and Coagulopathy 1052 Robert I Parker 104 Acquired Immune Dysfunction 1229 Brent J Pfeiffer 90 Thrombosis in Pediatric Critical Care 1073 Sally Campbell and Paul Monagle 105 Immune Balance in Critical Illness 1242 Mark W Hall 91 Transfusion Medicine 1082 Jacques Lacroix, Marisa Tucci, Oliver Karam, and Philip C Spinella 92 Hematology and Oncology Problems 1101 Jesse Wenger, Corinne Summers, and Joan S Roberts 106 Pediatric Rheumatologic Disease 1249 Marla Guzman, Timothy Hahn, Alexandra Aminoff, and Kristen Hayward 107 Bacterial and Fungal Infections 1263 Deborah E Franzon, Emily R Levy, and Matt S Zinter 93 Critical Illness in Children Undergoing Hematopoietic Progenitor Cell Transplantation 1113 Prakadeshwari Rajapreyar, Jennifer McArthur, Christine Duncan, Rachel Phelan, Robert T Tamburro Jr 108 Life-Threatening Viral Diseases and Their Treatment 1273 Surabhi B Vora, Alpana Waghmare, Danielle M Zerr, and Ann J Melvin Contents 109 Healthcare-Associated Infections 1284 Alexis L Benscoter, Richard J Brilli, Derek S Wheeler, and Erika L Stalets 110 Pediatric Sepsis 1293 Matthew N Alder, Lauren Bodilly, and Hector R Wong 111 Multiple-Organ Dysfunction Syndrome 1310 xxxi 124 Adverse Drug Reactions and Drug-Drug Interactions 1464 Jessie O’Neal, Lauren Dartois, Anny Chan, Wade W Benton, and Christa Jefferis Kirk 125 Principles of Toxin Assessment and Screening 1486 April Clawson and Lawrence Quang Pierre Tissieres and Melania M Bembea 126 Toxidromes and Their Treatment 1496 Section XII: Pediatric Critical Care: Environmental Injury and Trauma 1317 112 Bites and Stings 1318 Kirsten Orloff and Kanecia Zimmerman 113 Hyperthermic Injury 1327 Jason A Clayton and Philip Toltzis 114 Accidental Hypothermia 1332 Björn Gunnarsson and Christopher M.B Heard 115 Drowning 1337 Jamie L Bell, Ajit A Sarnaik, and Ashok P Sarnaik 116 Burn and Inhalation Injury 1347 Christian Tapking, Linda E Sousse, Karel D Capek, and David N Herndon 117 Evaluation, Stabilization, and Initial Management After Trauma 1363 Jessica A Naiditch, Michael Dingeldein, and David Tuggle 118 Traumatic Brain Injury 1375 Patrick M Kochanek, Michael J Bell, Dennis W Simon, Hülya Bayır, Jessica S Wallisch, Michael L Forbes, Randall Ruppel, P David Adelson, Travis C Jackson, and Robert S.B Clark 119 Pediatric Thoracic Trauma 1401 Tamara N Fitzgerald and Christopher R Reed 120 Pediatric Abdominal Trauma 1408 Adam M Vogel and Michael Dingeldein 121 Child Abuse 1417 Tom Kallay and Carol Berkowitz Section XIII: Pediatric Critical Care: Pharmacology and Toxicology 1425 122 Principles of Drug Disposition 1426 Nicole R Zane and Athena F Zuppa 123 Molecular Mechanisms of Drug Actions 1446 Kevin Watt Prashant Joshi Section XIV: Pediatric Critical Care: Anesthesia Principles in the Pediatric Intensive Care Unit 1509 127 Airway Management 1510 Chinyere Egbuta, E Alexis Bragg, and Sapna R Kudchadkar 128 Anesthesia Effects on Organ Systems 1535 Lindsay M Stollings, Peter J Davis, Alison M Ellis, and Antonio Cassara 129 Anesthesia Principles and Operating Room Anesthesia Regimens 1544 Joseph D Tobias 130 Malignant Hyperthermia 1560 Christopher M Edwards and Barbara W Brandom 131 Neuromuscular Blocking Agents 1567 Joseph D Tobias 132 Sedation and Analgesia 1583 Christopher M B Heard, Omar Alibrahim, and Alexandre T Rotta 133 Tolerance, Dependency, and Withdrawal 1611 Joseph D Tobias 134 Pediatric Delirium 1617 Chani Traube and Bruce M Greenwald 135 Procedural Sedation for the Pediatric Intensivist 1624 Nir Atlas, Rahul C Damania, and Pradip P Kamat Section XV: Pediatric Critical Care: Board Review Questions e1 136 Board Review Questions e2 Index 1629 SECTION I Pediatric Critical Care: The Discipline History of Pediatric Critical Care Medicine, 2 High-Reliability Pediatric Intensive Care Unit: Role of Intensivist and Team in Obtaining Optimal Outcomes, 16 Critical Communications in the Pediatric Intensive Care Unit, 22 Professionalism in Pediatric Critical Care, 26 Leading and Managing Change in the Pediatric Intensive Care Unit, 29 Evolution of Critical Care Nursing, 36 Fostering a Learning Healthcare Environment in the Pediatric Intensive Care Unit, 47 Challenges of Pediatric Critical Care in Resource-Poor Settings, 51 Public Health Emergencies and Emergency Mass Critical Care, 59 10 Lifelong Learning in Pediatric Critical Care, 66 ... Julie Blatt 87 The Erythron 1033 Allan Doctor, Ahmed Said, and Stephen Rogers 88 Hemoglobinopathies 1040 M.A Bender and Anne Marsh Samiran Ray, Rachel S Agbeko, and Mark J Peters Jennifer A