Báo cáo y học: " Attenuated allergic airway hyperresponsiveness in C57BL/6 mice is associated with enhanced surfactant protein (SP)-D production following allergic sensitization" pdf
... Access Research Attenuated allergic airway hyperresponsiveness in C57BL/6 mice is associated with enhanced surfactant protein (SP)-D production following allergic sensitization Elena N Atochina, Michael ... that enhanced SP-D production in the lung of C57BL/6 mice may contribute to an attenuated AHR in response to allergic airway sensitiza...
Ngày tải lên: 12/08/2014, 18:21
... arthritis and anti- glucose-6-phosphate isomerase (GPI) antibody induced arthritis [2,3], suggesting that FcγRIII is indispensible in autoantibody dependent arthritis. In humans FcγRs are encoded by ... conceived the study. HZ per- formed FcγR genotyping and coordinated the statistical analy- sis. YM, TY and YK performed GPI ELISA. TH participated in clinical assessment. TS participat...
Ngày tải lên: 09/08/2014, 07:20
... pulmonary disease (COPD) is characterized by a chronic inflammatory process, in which the pro-inflammatory cytokine Tumor Necrosis Factor (TNF)-α is considered to play a role. In the present study ... been detected in sputum [ 27] and in circulation [28] of COPD patients, indicating that this cytokine is involved in both the local and systemic inflammation present in CO...
Ngày tải lên: 12/08/2014, 18:20
Báo cáo y học: "HLA-C increases HIV-1 infectivity and is associated with gp120" pot
... possibility that some HLA-C allelic variants may be more efficient than others in binding Env and enhancing viral infectivity. An implication of these findings is that HLA-C may be selectively involved ... silenced by small interfering RNA sequences. Syncytia formation was analyzed by co-cultivating cell lines expressing HIV-1 gp120/gp41 from different laboratory and primary isolates wit...
Ngày tải lên: 13/08/2014, 05:21
Báo cáo y học: "Prolonged N-acetylcysteine therapy in late acetaminophen poisoning associated with acute liver failure – a need to be more cautious" docx
... [1]. N -acetylcysteine in acetaminophen poisoning and acetaminophen-induced liver failure NAC has been used since the 1970s, and it effectively manages APAP poisoning by glutathione repletion if adminis- tered ... hepato- toxicity’ by Yang and colleagues [1], published in the previous issue of Critical Care, demonstrates that prolonged administration of N-acetylcysteine (NAC) at 100 mg/kg...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo y học: "4G/5G polymorphism of PAI-1 gene is associated with multiple organ dysfunction and septic shock in pneumonia induced severe sepsis: prospective, observational, genetic study" doc
... glycoprotein serine protease plasminogen activator inhibitor-1 (PAI-1) is a key element in the inhibition of fibrinolysis. The primary role of PAI-1 in vivo is fast act- ing inhibition of tissue- ... with the 5G/5G genotype verifying that this polymorphism may influence outcome of sepsis through the disturbance of coagulation. This result was in agreement with the study by Binde...
Ngày tải lên: 13/08/2014, 20:22
Báo cáo y học: " Increased serum soluble Fas after major trauma is associated with delayed neutrophil apoptosis and development of sepsis" pot
... [32], thus promoting intrinsic apoptosis resis- tance in neutrophils [28]. The Fas/FasL system plays a key role in maintaining the homeostasis of the immune system. It is widely accepted that ... activity of sFas in combination with the previously reported impaired intrinsic apoptosis pathway in neutrophils after trauma might be an impor- tant factor in the ongoing inflammatory...
Ngày tải lên: 14/08/2014, 07:21
Báo cáo y học: "Quantitative expression of osteopontin in nasal mucosa of patients with allergic rhinitis: effects of pollen exposure and nasal glucocorticoid treatment" pdf
... inflammatory process in allergic rhinitis (AR) involves many different inflammatory cells, cytokines, chemokines and other regulatory molecules [1]. It is well known that exposure to allergens, including ... 0.82). Discussion There is an increased scientific interest in the putative role of OPN in several diseases, including asthma, allergy and rhinosinusitis [7,10,14,15]. In th...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "Clinical review: Airway hygiene in the intensive care unit" pptx
... airway hygiene. β 2 -Adrenergic agonists increase ciliary beat frequency in experimental models, raising the possibility that they may be useful for airway hygiene [99]. Salbutamol increases large- airway mucociliary clearance, ... teaching pulmonologists -in- training that there is rarely a role for bronchoscopy for atelectasis. In addition, bronchoscopy in patients with acut...
Ngày tải lên: 13/08/2014, 08:21
Báo cáo y học: "Genetic polymorphism of p53, but not GSTP1, is association with susceptibility to esophageal cancer risk – A Meta-Analysis"
... are con- sistent with our present meta-analysis study. Thus, it is reasonable to hypothesize that the Arg72Pro poly- morphism with reduced activity of p53 may play more important role in esophageal ... interactive with some lifestyle and dietary habits, but is not a signifi- cant independent susceptibility factor. The p53 tumor suppressor pathway is well-known to be crucial...
Ngày tải lên: 25/10/2012, 11:40