... MINIREVIEW Huntington’s disease: roles of huntingtin-interacting protein 1 (HIP -1) and its molecular partner HIPPI in the regulation of apoptosis and transcription Nitai P. ... chain B; ENTH, Epsin N-terminal homology; HD, Huntington’s disease; HIP -1, huntingtin-interacting protein 1; HIPPI, huntingtin-interacting protein 1 interactor; Htt, huntingtin protein; NMDAR, N-methyl-D-aspartate ... of Htt-interacting protein HIP -1 and its molecular part-ner HIPPI in the regulation of apoptosis and transcrip-tion, the two processes that are altered in HD [7,8].HIP -1 – its interacting partners...