Báo cáo y học: "Quantifying the mechanisms of domain gain in animal proteins" doc

... for the high-confidence domain gains differs from the number of gained domains. Additional file 3: Distribution of domain gain events according to the position of the domain insertion and the ... number of exons gained in the set of high-confidence domain gains and the set of medium-confidence domain gains. (a) The distribution of characteristics o...

Ngày tải lên: 09/08/2014, 20:22

... expression of many genes and any given gene is typically regulated by at most a handful of transcription factors (TFs) [1]. Some studies in animals, including studies of the early development of Drosophila, ... extension of the concept of a small number of highly specific TFs that define expression domains. Recent studies, including one by Adryan and Teichmann in thi...

Ngày tải lên: 09/08/2014, 20:21

... parts of the network, whereas the instability of the stationary state originates from PFK and the ATP-ADP-AMP system. The mechanism of glycolytic oscillations in yeast extracts In the case of yeast ... a contemporary point of view, the theoretical motivation for the application of the crossover theorem in the analysis of glycolytic oscillations is weak...

Ngày tải lên: 30/03/2014, 16:20

... score of 54 points was possible). Panel C plots the log of MSJ ratio against the SIAS scores. Panel D plots the log of the MSJ ratio against FMA-UE. The dashed line shows the linear fitting of the ... is often difficult to clearly iden- tify the timing of movement initiation and termination because of the irregularity of the movement [29]. There- fore, Median...

Ngày tải lên: 19/06/2014, 08:20

... 42% of children were diagnosed with AR by the age of 6 years. The prevalence of AR has increased dramatically in the past 30 years and continues to increase. Children with one component of atopy ... risk of developing a second component. 2 In 1998, the Joint Task Force on Practice Parameters in Allergy, Asthma, and Immunology defined rhinitis as ‘‘inflammation of th...

Ngày tải lên: 08/08/2014, 21:20

... obesity, gout is becoming endemic in China. Finally, symptomatic knee osteoarthritis is extremely common in China and constitutes a major public health problem there. In the present issue of Arthritis ... prevalence would often be more informative, especially since rheumatic diseases vary in prevalence by age. An additional source of Editorial Comparing the prevalence of rhe...

Ngày tải lên: 09/08/2014, 10:22

... another identical embedding of the same graph in the same surface and call it Ψ  0 . Again this time we will first modify the underlying graphs of the two embeddings, and then proceed to link the ... vertices of v 1 ,andthey are labeled as v i ’s on the face boundary of F 0 . Again, make precisely the same selection of faces in Ψ  . Then, for each i =1, ,l− 1, ins...

Ngày tải lên: 07/08/2014, 07:21

... expression in the cells (Figure 3B). In the contrary, PAR2-IP may bind to trypsin with high affinity, and consequently inhibits its digesting activity. Recent studies have demonstrated that trypsin- ... with the PAR2-IP at 75 μM, the trypsin-induced phosphorylation of p65 was inhibited in both cell types (Figure 5B). These results suggest that the PAR2-IP inhibited trypsin-i...

Ngày tải lên: 10/08/2014, 05:21

... goal of identifying and treating patients early in the course of their illness is preferable to waiting until more serious signs and symptoms have developed. Certainly, at the University of ... from baseline to the study period for both groups combined. Conclusion The MET system greatly increases emergency team calling, but does not substantially affect the incidence...

Ngày tải lên: 25/10/2012, 10:39

... E a almost the same as in the case ofthenativeenzyme(Table1). Thermal inactivation of mutant and wild-type enzymes In order to investigate the effects of mutations on the stability of psychrophilic ... resulted in an enzyme with slightly lower stability. On the other hand, in the double mutant G261A /Y2 69A the additional replacement of Tyr269 by Ala restores th...

Ngày tải lên: 22/02/2014, 04:20